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lactobacillus LS
Lactobacillus LS is a probiotic strain that modulates the gut microbiota and enhances intestinal barrier function and immune response.
Lactobacillus LS is a probiotic strain that modulates the gut microbiota and enhances intestinal barrier function and immune response. Used for Gastrointestinal disorders (specific indication in Phase 3 trial not publicly detailed).
At a glance
| Generic name | lactobacillus LS |
|---|---|
| Sponsor | Ain Shams University |
| Drug class | Live biotherapeutic product / Probiotic |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology / Immunology |
| Phase | Phase 3 |
Mechanism of action
This live biotherapeutic product works by colonizing the gastrointestinal tract, producing beneficial metabolites, and promoting the growth of commensal bacteria while inhibiting pathogenic organisms. It strengthens the intestinal epithelial barrier through tight junction protein expression and stimulates local and systemic immune responses via pattern recognition receptors on intestinal immune cells.
Approved indications
- Gastrointestinal disorders (specific indication in Phase 3 trial not publicly detailed)
Common side effects
- Gastrointestinal disturbances (bloating, gas, mild diarrhea)
- Abdominal discomfort
Key clinical trials
- Modulation of Gut Microbiota Composition and Gut Permeability Profiles by Multispecies Synbiotic Supplementation in Hemodialysis Patients (NA)
- Alterations of Gut Derived Uremic Toxins and Microbiome Metabolites by Multispecies Synbiotic (NA)
- : EFFECT OF PROBIOTIC SUPPLEMENTATION ON ATYPICAL ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN PATIENTS ATTENDING PSYCHIATRIC CLINICS AT AINSHAMS UNIVERSITY HOSPITALS (A RANDOMIZED CONTROLLED TRIAL) (PHASE3)
- Probiotic Supplementation IN NAFLD Patients (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- lactobacillus LS CI brief — competitive landscape report
- lactobacillus LS updates RSS · CI watch RSS
- Ain Shams University portfolio CI