Last reviewed 2026-04-22 · How we verify

lactobacillus LB

Lactobacillus LB is a probiotic bacterium that modulates the gut microbiota and intestinal immune function to promote gastrointestinal health.

Lactobacillus LB is a probiotic bacterium that modulates the gut microbiota and intestinal immune function to promote gastrointestinal health. Used for Gastrointestinal health maintenance, Microbiota restoration.

At a glance

Mechanism of action

This live biotherapeutic product colonizes the intestinal tract and produces metabolites that support beneficial microbiota composition, enhance intestinal barrier function, and promote local and systemic immune tolerance. By restoring or maintaining healthy microbial balance, it may reduce pathogenic bacterial overgrowth and associated inflammatory responses.

Approved indications

• Gastrointestinal health maintenance
• Microbiota restoration

Common side effects

• Gastrointestinal disturbance (bloating, gas)
• Mild abdominal discomfort

Key clinical trials

• Effect of Daily Humiome® Post LB Intake on Wellbeing in Older Individuals With Moderate Stress Levels (NA)
• Study Evaluating the Effect of Humiome® Post LB on Stress, Anxiety, and Cognition in Aging Adults (NA)
• The Effect of Humiome® Post LB on Gut COMFort in healthY Adult Volunteers (NA)
• Probiotics in Systemic Lupus Erythematosus (PHASE2)
• Lactobacillus LB as Treatment for Irritable Bowel Syndrome With Predominance of Diarrhea (IBS-D) (PHASE4)
• Assessment of Probiotics Lactobacillus in the Management of Attention Deficit Hyperactive Disorder (EARLY_PHASE1)
• Research on the Characteristics and Application of Lactobacillus Rhamnosus X253 as Oral Probiotics (NA)
• A Study on Efficacy of Feeding N1115 Probiotic Supplement to Young Children (NA)

Primary sources

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