What are the marketed Intravenous anesthetic combination (hypnotic + opioid) drugs?

Marketed Intravenous anesthetic combination (hypnotic + opioid) drugs include Propofol and Alfentanil, Sedation Etomidate combined with propofol, Propofol/Lidocaine, Propofol + Alfentanil, ketamine and propofol.

Intravenous anesthetic combination (hypnotic + opioid)

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

5 marketed 1 in Phase 3

This page covers all Intravenous anesthetic combination (hypnotic + opioid) drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting GABA-A receptor (propofol); mu opioid receptor (alfentanil), GABA-A receptor, GABA-A receptor (propofol); voltage-gated sodium channels (lidocaine).

Targets

GABA-A receptor (propofol); mu opioid receptor (alfentanil) · GABA-A receptor · GABA-A receptor (propofol); voltage-gated sodium channels (lidocaine) · GABA-A receptor (propofol); mu-opioid receptor (alfentanil) · NMDA receptor (ketamine); GABA-A receptor (propofol) · GABA-A receptor (propofol); mu-opioid receptor (remifentanil)

Marketed (5)

Propofol and Alfentanil · North District Hospital · Anesthesiology
Propofol and alfentanil together provide rapid induction and maintenance of general anesthesia through GABA receptor potentiation and opioid receptor activation, respectively.
Sedation Etomidate combined with propofol · RenJi Hospital · Anesthesia
A combination of two intravenous anesthetic agents that work synergistically to produce rapid sedation and hypnosis through GABAergic and other central nervous system pathways.
Propofol/Lidocaine · NYU Langone Health · Anesthesiology
Propofol and lidocaine together provide rapid induction and maintenance of anesthesia with reduced pain on injection through synergistic central nervous system depression.
Propofol + Alfentanil · Region Jönköping County · Anesthesiology
Propofol and alfentanil together provide rapid induction and maintenance of general anesthesia through synergistic central nervous system depression.
ketamine and propofol · Ain Shams University · Anesthesiology
This is a combination of two intravenous anesthetic agents that work synergistically to produce rapid sedation and anesthesia through different mechanisms.

Phase 3 pipeline (1)

Propofol + Remifentanyl · Azienda Ospedaliera San Gerardo di Monza · Anesthesiology
Propofol and remifentanil together provide rapid-onset sedation and analgesia by depressing the central nervous system through GABA potentiation and opioid receptor agonism, respectively.

Patent intelligence

intravenous anesthetic combination patent landscape — aggregated cliff calendar, attackable patents, originator estates