What are First-generation cephalosporin drugs?

First-generation cephalosporin drugs are pharmacologic agents that share a common mechanism (typically targeting Penicillin-binding proteins (PBPs)). 9 are currently marketed, with 0 more in clinical development.

What are the marketed First-generation cephalosporin drugs?

Marketed First-generation cephalosporin drugs include Cefadroxil until drain removal, Cefadroxil tablets manufactured by NP, Cefazolin Preoperatively, Bolus dose of Cefazolin, Cefadroxil tablets manufactured by GSK, Cefadroxil discontinued early.

First-generation cephalosporin

9 marketed

This page covers all First-generation cephalosporin drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Penicillin-binding proteins (PBPs).

Targets

Penicillin-binding proteins (PBPs)

Marketed (9)

Cefadroxil until drain removal · Stony Brook University · Infectious Disease
Cefadroxil is a first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
Cefadroxil tablets manufactured by NP · GlaxoSmithKline · Infectious Disease
Cefadroxil is a first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and cross-linking peptidoglycan strands.
Cefazolin Preoperatively · Aultman Health Foundation · Infectious Disease
Cefazolin is a first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
Bolus dose of Cefazolin · University of Florida · Infectious Disease
Cefazolin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking cross-linking of peptidoglycan.
Cefadroxil tablets manufactured by GSK · GlaxoSmithKline · Infectious Disease
Cefadroxil inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and cross-linking peptidoglycan strands.
Cefadroxil discontinued early · Stony Brook University · Infectious Disease
Cefadroxil is a first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
Cefazolin PostOperatively · Aultman Health Foundation · Infectious Disease
Cefazolin is a first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
Cefazolin 2 GM Injection · Abdul El-Rabbany · Infectious Disease
Cefazolin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking cross-linking of peptidoglycan.
CEPHALEXIN · Immunology
Cephalexin is a cephalosporin antibacterial drug.