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Cefadroxil until drain removal
Cefadroxil until drain removal is a First-generation cephalosporin Small molecule drug developed by Stony Brook University. It is currently FDA-approved for Surgical site infection prophylaxis until drain removal, Bacterial infections (skin and soft tissue, urinary tract, respiratory tract). Also known as: Duricef, Cefazolin, Ancef, Clindamycin.
Cefadroxil is a first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
Cefadroxil is a small molecule that inhibits bacterial penicillin-binding protein, classified as an INHIBITOR. It is used to treat bacterial infections, as indicated by its study on postoperative antibiotic requirements following immediate breast reconstruction.
At a glance
| Generic name | Cefadroxil until drain removal |
|---|---|
| Also known as | Duricef, Cefazolin, Ancef, Clindamycin, Cleocin |
| Sponsor | Stony Brook University |
| Drug class | First-generation cephalosporin |
| Target | Penicillin-binding proteins (PBPs) |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Cefadroxil works by disrupting the cross-linking of peptidoglycan in bacterial cell walls, leading to cell wall instability and bacterial death. It is bactericidal and has broad-spectrum activity against gram-positive and some gram-negative bacteria. The notation 'until drain removal' suggests this is a prophylactic or therapeutic use in a surgical context, likely to prevent infection until a surgical drain is removed.
Approved indications
- Surgical site infection prophylaxis until drain removal
- Bacterial infections (skin and soft tissue, urinary tract, respiratory tract)
Common side effects
- Diarrhea
- Nausea
- Rash
- Allergic reaction
- Pseudomembranous colitis
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Cefadroxil until drain removal CI brief — competitive landscape report
- Cefadroxil until drain removal updates RSS · CI watch RSS
- Stony Brook University portfolio CI
Frequently asked questions about Cefadroxil until drain removal
What is Cefadroxil until drain removal?
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What is Cefadroxil until drain removal used for?
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Is Cefadroxil until drain removal also known as anything else?
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What does Cefadroxil until drain removal target?
Related
- Drug class: All First-generation cephalosporin drugs
- Target: All drugs targeting Penicillin-binding proteins (PBPs)
- Manufacturer: Stony Brook University — full pipeline
- Therapeutic area: All drugs in Infectious Disease
- Indication: Drugs for Surgical site infection prophylaxis until drain removal
- Indication: Drugs for Bacterial infections (skin and soft tissue, urinary tract, respiratory tract)
- Also known as: Duricef, Cefazolin, Ancef, Clindamycin, Cleocin
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing