Who are Tramadol OAD's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Tramadol IV (Tradonal® IV), Tramadol /acetaminophen, Tramal®, Tramadol HCl, Tramadol PR oral, Tramadol 50.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Tramadol OAD — Competitive Intelligence Brief

Tramadol OAD (Tramadol OAD) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Opioid analgesic with norepinephrine-serotonin reuptake inhibition. Area: Pain Management.

phase 3 Opioid analgesic with norepinephrine-serotonin reuptake inhibition Mu opioid receptor; norepinephrine transporter; serotonin transporter Pain Management Small molecule Live · refreshed every 30 min

Target snapshot

Tramadol OAD (Tramadol OAD) — Labopharm Inc.. Tramadol is an opioid analgesic that binds to mu opioid receptors and also inhibits the reuptake of norepinephrine and serotonin to provide pain relief.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Tramadol OAD TARGET	Tramadol OAD	Labopharm Inc.	phase 3	Opioid analgesic with norepinephrine-serotonin reuptake inhibition	Mu opioid receptor; norepinephrine transporter; serotonin transporter
Tramadol IV (Tradonal® IV)	Tramadol IV (Tradonal® IV)	University Hospital, Ghent	marketed	Opioid analgesic with monoamine reuptake inhibition	Mu opioid receptor; norepinephrine transporter; serotonin transporter
Tramadol /acetaminophen	Tramadol /acetaminophen	Johnson & Johnson Taiwan Ltd	marketed	Opioid analgesic combination	Mu opioid receptor; norepinephrine transporter; serotonin transporter; cyclooxygenase
Tramal®	Tramal®	Apsen Farmaceutica S.A.	marketed	Synthetic opioid analgesic	Mu opioid receptor; norepinephrine transporter; serotonin transporter
Tramadol HCl	Tramadol HCl	Labopharm Inc.	marketed	Synthetic opioid analgesic with monoamine reuptake inhibition	Mu opioid receptor; norepinephrine transporter; serotonin transporter
Tramadol PR oral	Tramadol PR oral	Pfizer	phase 3	Opioid analgesic with monoamine reuptake inhibition	Mu opioid receptor; norepinephrine transporter; serotonin transporter
Tramadol 50	Tramadol 50	Grünenthal GmbH	phase 3	Synthetic opioid analgesic	Mu opioid receptor; norepinephrine transporter; serotonin transporter

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Opioid analgesic with norepinephrine-serotonin reuptake inhibition class)

Labopharm Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tramadol OAD — Competitive Intelligence Brief. https://druglandscape.com/ci/tramadol-oad. Accessed 2026-05-14.

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