Who are Systane Ultra Preservative Free's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Rohto Dry-Aid®, Systane Hydration PF, Meticel Ofteno® 0.5%, Lipid-Based Artificial Tear, Meticel Ofteno®, Prosicca sine.

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Last reviewed 2026-05-17 · How we verify

Systane Ultra Preservative Free — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Systane Ultra Preservative Free (Systane Ultra Preservative Free) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Artificial tear / Ocular lubricant. Area: Ophthalmology.

marketed Artificial tear / Ocular lubricant Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Systane Ultra Preservative Free (Systane Ultra Preservative Free) — Laboratorios Sophia S.A de C.V.. Systane Ultra Preservative Free is an artificial tear solution that lubricates and protects the ocular surface to relieve dry eye symptoms.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class
Systane Ultra Preservative Free TARGET	Systane Ultra Preservative Free	Laboratorios Sophia S.A de C.V.	marketed	Artificial tear / Ocular lubricant
Rohto Dry-Aid®	Rohto Dry-Aid®	The Mentholatum Company	marketed	Artificial tear / ocular lubricant
Systane Hydration PF	Systane Hydration PF	University of Alabama at Birmingham	marketed	Artificial tear / Ocular lubricant
Meticel Ofteno® 0.5%	Meticel Ofteno® 0.5%	Laboratorios Sophia S.A de C.V.	marketed	Artificial tear / Ocular lubricant
Lipid-Based Artificial Tear	Lipid-Based Artificial Tear	University of Seville	marketed	Artificial tear / Ocular lubricant
Meticel Ofteno®	Meticel Ofteno®	Laboratorios Sophia S.A de C.V.	marketed	Artificial tear / Ocular lubricant
Prosicca sine	Prosicca sine	Medical University of Vienna	marketed	Artificial tear / ocular lubricant

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Artificial tear / Ocular lubricant class)

Laboratorios Sophia S.A de C.V. · 7 drugs in this class
Allergan · 3 drugs in this class
University of Waterloo · 2 drugs in this class
University of California, Berkeley · 2 drugs in this class
Bp Consulting, Inc · 1 drug in this class
Chong Kun Dang Pharmaceutical · 1 drug in this class
Clinica Oftamologica Zona Sul · 1 drug in this class
Fundação Altino Ventura · 1 drug in this class
Medical University of South Carolina · 1 drug in this class
Ocuwize LTD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Systane Ultra Preservative Free — Competitive Intelligence Brief. https://druglandscape.com/ci/systane-ultra-preservative-free. Accessed 2026-05-17.

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