Last reviewed 2026-04-22 · How we verify

Meticel Ofteno® 0.5%

Meticel Ofteno is a topical ophthalmic solution containing methylcellulose that acts as a lubricating and protective agent for the ocular surface.

Meticel Ofteno is a topical ophthalmic solution containing methylcellulose that acts as a lubricating and protective agent for the ocular surface. Used for Dry eye syndrome / Keratoconjunctivitis sicca, Ocular surface protection and lubrication.

At a glance

Mechanism of action

Methylcellulose is a cellulose derivative that functions as an artificial tear substitute and ocular lubricant. It increases tear film viscosity and stability, protecting the corneal and conjunctival epithelium from desiccation and mechanical irritation. The formulation helps maintain ocular surface hydration and provides a protective barrier.

Approved indications

• Dry eye syndrome / Keratoconjunctivitis sicca
• Ocular surface protection and lubrication

Common side effects

• Transient blurred vision
• Eye irritation
• Mild ocular discomfort

Key clinical trials

• Evaluation of Manzanilla® and Meticel Ofteno® 0.5% for Providing a Relief Sensation to the Eyes (PHASE4)
• Study of Non-inferiority Between Manzanilla Sophia® and Meticel Ofteno® 0.5% for Providing a Soothing Sensation to the Eyes. (PHASE4)

Primary sources

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Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Meticel Ofteno® 0.5% CI brief — competitive landscape report
• Meticel Ofteno® 0.5% updates RSS · CI watch RSS
• Laboratorios Sophia S.A de C.V. portfolio CI