{"id":"meticel-ofteno-0-5","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient blurred vision"},{"rate":null,"effect":"Eye irritation"},{"rate":null,"effect":"Mild ocular discomfort"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Methylcellulose is a cellulose derivative that functions as an artificial tear substitute and ocular lubricant. It increases tear film viscosity and stability, protecting the corneal and conjunctival epithelium from desiccation and mechanical irritation. The formulation helps maintain ocular surface hydration and provides a protective barrier.","oneSentence":"Meticel Ofteno is a topical ophthalmic solution containing methylcellulose that acts as a lubricating and protective agent for the ocular surface.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:34:31.664Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye syndrome / Keratoconjunctivitis sicca"},{"name":"Ocular surface protection and lubrication"}]},"trialDetails":[{"nctId":"NCT06859476","phase":"PHASE4","title":"Evaluation of Manzanilla® and Meticel Ofteno® 0.5% for Providing a Relief Sensation to the Eyes","status":"COMPLETED","sponsor":"Laboratorios Sophia S.A de C.V.","startDate":"2025-05-23","conditions":"Ophthalmological Agent Toxicity","enrollment":168},{"nctId":"NCT06373653","phase":"PHASE4","title":"Study of Non-inferiority Between Manzanilla Sophia® and Meticel Ofteno® 0.5% for Providing a Soothing Sensation to the Eyes.","status":"WITHDRAWN","sponsor":"Laboratorios Sophia S.A de C.V.","startDate":"2025-02-11","conditions":"Eye Strain, Eye Strain of Both Eyes","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Meticel Ofteno® 0.5%","genericName":"Meticel Ofteno® 0.5%","companyName":"Laboratorios Sophia S.A de C.V.","companyId":"laboratorios-sophia-s-a-de-c-v","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Meticel Ofteno is a topical ophthalmic solution containing methylcellulose that acts as a lubricating and protective agent for the ocular surface. Used for Dry eye syndrome / Keratoconjunctivitis sicca, Ocular surface protection and lubrication.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}