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Prosicca sine

Medical University of Vienna · FDA-approved active Small molecule

Prosicca sine is a mucin-based bioadhesive formulation designed to provide sustained lubrication and protection to the ocular surface in dry eye disease.

Prosicca sine is a mucin-based bioadhesive formulation designed to provide sustained lubrication and protection to the ocular surface in dry eye disease. Used for Severe dry eye syndrome / keratoconjunctivitis sicca.

At a glance

Generic nameProsicca sine
SponsorMedical University of Vienna
Drug classArtificial tear / ocular lubricant
ModalitySmall molecule
Therapeutic areaOphthalmology
PhaseFDA-approved

Mechanism of action

The drug consists of a mucin-containing polymer that adheres to the corneal and conjunctival epithelium, forming a protective layer that reduces friction, maintains moisture, and protects against further epithelial damage. By mimicking natural tear film components, it provides symptomatic relief and supports ocular surface healing in patients with severe dry eye syndrome.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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