Who are Sulfadoxine-pyrimethamine used for IPTi's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Sulfamethoxazole-Trimethoprim, Sulfamethoxazole Trimethoprim Combination, IPTp-SP, Intermittent preventive treatment:sulphadoxine-pyrimethamine, sulfadoxine pyrimethamine plus piperaquine, sulfadoxine-pyrimethamine and chlorproguanil-dapsone.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

How do I get this as a recurring report?

Subscribe to /feed/ci/sulfadoxine-pyrimethamine-used-for-ipti.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-17 · How we verify

Sulfadoxine-pyrimethamine used for IPTi — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Sulfadoxine-pyrimethamine used for IPTi (Sulfadoxine-pyrimethamine used for IPTi) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antifolate antimalarial combination. Area: Infectious Disease.

phase 3 Antifolate antimalarial combination Dihydropteroate synthase; Dihydrofolate reductase Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

Sulfadoxine-pyrimethamine used for IPTi (Sulfadoxine-pyrimethamine used for IPTi) — Swiss Tropical & Public Health Institute. Sulfadoxine-pyrimethamine is a fixed-dose combination of two antifolate drugs that inhibits dihydrofolate reductase and dihydropteroate synthase, blocking folate synthesis in malaria parasites.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Sulfadoxine-pyrimethamine used for IPTi TARGET	Sulfadoxine-pyrimethamine used for IPTi	Swiss Tropical & Public Health Institute	phase 3	Antifolate antimalarial combination	Dihydropteroate synthase; Dihydrofolate reductase
Sulfamethoxazole-Trimethoprim	Sulfamethoxazole-Trimethoprim	National Institute of Allergy and Infectious Diseases (NIAID)	marketed	Sulfonamide-dihydrofolate reductase inhibitor combination	Dihydropteroate synthase; Dihydrofolate reductase
Sulfamethoxazole Trimethoprim Combination	Sulfamethoxazole Trimethoprim Combination	Baylor Research Institute	marketed	Sulfonamide-dihydrofolate reductase inhibitor combination	Dihydropteroate synthase; Dihydrofolate reductase
IPTp-SP	IPTp-SP	Kenya Medical Research Institute	marketed	Antifolate antimalarial combination	Dihydrofolate reductase (DHFR)
Intermittent preventive treatment:sulphadoxine-pyrimethamine	Intermittent preventive treatment:sulphadoxine-pyrimethamine	London School of Hygiene and Tropical Medicine	phase 3	Antifolate antimalarial combination	Dihydropteroate synthase and dihydrofolate reductase
sulfadoxine pyrimethamine plus piperaquine	sulfadoxine pyrimethamine plus piperaquine	London School of Hygiene and Tropical Medicine	phase 3	Antifolate antimalarial combination with quinoline antimalarial	Plasmodium dihydrofolate reductase, dihydropteroate synthase, and parasite mitochondria
sulfadoxine-pyrimethamine and chlorproguanil-dapsone	sulfadoxine-pyrimethamine and chlorproguanil-dapsone	London School of Hygiene and Tropical Medicine	phase 3	Antifolate antimalarial combination	Dihydrofolate reductase; dihydropteroate synthase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antifolate antimalarial combination class)

London School of Hygiene and Tropical Medicine · 4 drugs in this class
Kenya Medical Research Institute · 1 drug in this class
Swiss Tropical & Public Health Institute · 1 drug in this class

Subscribe to ongoing alerts

Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:

Cite this brief

Drug Landscape (2026). Sulfadoxine-pyrimethamine used for IPTi — Competitive Intelligence Brief. https://druglandscape.com/ci/sulfadoxine-pyrimethamine-used-for-ipti. Accessed 2026-05-17.

Build your own brief

Pick any drug + add comparators:

https://druglandscape.com/ci/{slug} — auto-detected competitors
https://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3 — explicit comparators
Brand names auto-resolve: /ci/keytruda → 301 → /ci/pembrolizumab