Ropivacaine with epinephrine injection — Competitive Intelligence Brief

Ropivacaine with epinephrine injection (Ropivacaine with epinephrine injection) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesiology.

phase 3 Local anesthetic Voltage-gated sodium channels Anesthesiology Small molecule

Target snapshot

Ropivacaine with epinephrine injection (Ropivacaine with epinephrine injection) — Seoul National University Hospital. Ropivacaine with epinephrine injection works by blocking nerve signals to provide local anesthesia and vasoconstriction.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Ropivacaine with epinephrine injection TARGET	Ropivacaine with epinephrine injection	Seoul National University Hospital	phase 3	Local anesthetic	Voltage-gated sodium channels
Paroxetine+Lamotrigine	Paroxetine+Lamotrigine	Ministry of Health & Welfare, Korea	marketed	SSRI + anticonvulsant mood stabilizer combination	Serotonin transporter (SERT); voltage-gated sodium channels; glutamate release modulation
Dose of prilocaine	Dose of prilocaine	Hospital General Universitario Gregorio Marañon	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Levobupivacaine wound infusion	Levobupivacaine wound infusion	University of Genova	marketed	Local anesthetic	Voltage-gated sodium channels
lamotrigine (brand Lamictal)	lamotrigine (brand Lamictal)	University of Maryland, Baltimore	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release inhibition
Paracetamol +caudal ropivacaine	Paracetamol +caudal ropivacaine	Aga Khan University	marketed	Analgesic combination (systemic + local anesthetic)	COX inhibition (paracetamol); voltage-gated sodium channels (ropivacaine)
Ropivacaine + Ketamine	Ropivacaine + Ketamine	Aga Khan University	marketed	Local anesthetic + NMDA receptor antagonist combination	Voltage-gated sodium channels (ropivacaine); NMDA receptor (ketamine)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class