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Ropivacaine with epinephrine injection
Ropivacaine with epinephrine injection works by blocking nerve signals to provide local anesthesia and vasoconstriction.
Ropivacaine with epinephrine injection works by blocking nerve signals to provide local anesthesia and vasoconstriction. Used for Regional anesthesia for surgical procedures, Pain management for postoperative patients.
At a glance
| Generic name | Ropivacaine with epinephrine injection |
|---|---|
| Also known as | Hanlim ropiva injection 7.5 mg/mL (20cc), Insurance code: A37804211, Jeil epinephrine injection 1 mg/mL (1cc), Insurance code: A04900341, Naropin |
| Sponsor | Seoul National University Hospital |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 3 |
Mechanism of action
Ropivacaine is a local anesthetic that selectively blocks sodium channels in nerve fibers, preventing the initiation and transmission of nerve impulses. The addition of epinephrine causes vasoconstriction, which prolongs the duration of anesthesia and reduces bleeding at the injection site.
Approved indications
- Regional anesthesia for surgical procedures
- Pain management for postoperative patients
Common side effects
- Nausea
- Vomiting
- Dizziness
- Headache
- Hypotension
Key clinical trials
- Mid-transverse Process Combined With Erector Spinae Block Versus Paravertebral Plane Block (NA)
- Popliteal Nerve Block for Acute Achilles Tendon Rupture Repair Surgery (NA)
- Functional Endoscopic Sinus Surgery Study (PHASE1, PHASE2)
- Tramadol / Magnesium in Ropivacaine Solution in UG-bilateral TAP Block and Analgesia in Robotic Radical Prostatectomy (NA)
- Connective Tissue Matrix Compared to Steroid Injections for Rotator Cuff Tendinopathy (NA)
- Frozen Shoulder and Hormone Replacement Therapy (PHASE4)
- PENG Block + LIA For Endoprosthesis Surgery With Anterior Approach (NA)
- Posthectomy in Pediatric Elective Surgery : a Comparison of Perioperative Analgesia Using Echo-guided Penile Block and Pudendal Block With neurostimuLation Technique (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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