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Ropivacaine irrigation — Competitive Intelligence Brief
phase 3
Local anesthetic
Voltage-gated sodium channels
Anesthesiology
Small molecule
Live · refreshed every 30 min
Target snapshot
Ropivacaine irrigation (Ropivacaine irrigation) — Hospital General Universitario Elche. Ropivacaine is a local anesthetic that works by blocking sodium channels in nerve fibers, preventing the initiation and transmission of nerve impulses.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ropivacaine irrigation TARGET | Ropivacaine irrigation | Hospital General Universitario Elche | phase 3 | Local anesthetic | Voltage-gated sodium channels | |
| Control (bupivacaine) | Control (bupivacaine) | Kasr El Aini Hospital | marketed | Local anesthetic (amide) | Voltage-gated sodium channels | |
| Lidocaine (drug) | Lidocaine (drug) | Daniel A Tonetti, MD | marketed | Local anesthetic | Voltage-gated sodium channels | |
| Hyperbaric bupivacaine+Morphine | Hyperbaric bupivacaine+Morphine | Fundación Pública Andaluza Progreso y Salud | marketed | Local anesthetic + opioid combination | Voltage-gated sodium channels (bupivacaine); mu opioid receptors (morphine) | |
| Bupivacaine (Marcaine) | Bupivacaine (Marcaine) | NYU Langone Health | marketed | Local anesthetic (amide) | Voltage-gated sodium channels | |
| lamotrigine (generic Teva) | lamotrigine (generic Teva) | University of Maryland, Baltimore | marketed | Anticonvulsant / Mood stabilizer | Voltage-gated sodium channels; glutamate release inhibition | |
| Lidocaine solution ("A") | Lidocaine solution ("A") | Hospital Universitari de Bellvitge | marketed | Local anesthetic | Voltage-gated sodium channels |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Local anesthetic class)
- University of California, San Diego · 3 drugs in this class
- Durect · 3 drugs in this class
- Pacira Pharmaceuticals, Inc · 3 drugs in this class
- Wake Forest University Health Sciences · 3 drugs in this class
- Medical University of Vienna · 3 drugs in this class
- Imperial College London · 2 drugs in this class
- Hvidovre University Hospital · 2 drugs in this class
- Innocoll · 2 drugs in this class
- George Washington University · 2 drugs in this class
- Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Ropivacaine irrigation — Competitive Intelligence Brief. https://druglandscape.com/ci/ropivacaine-irrigation. Accessed 2026-05-18.
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