Ropivacaine instillation — Competitive Intelligence Brief

Ropivacaine instillation (Ropivacaine instillation) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide). Area: Anesthesia / Pain Management.

phase 3 Local anesthetic (amide) Voltage-gated sodium channels Anesthesia / Pain Management Small molecule

Target snapshot

Ropivacaine instillation (Ropivacaine instillation) — San Gerardo Hospital. Ropivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Ropivacaine instillation TARGET	Ropivacaine instillation	San Gerardo Hospital	phase 3	Local anesthetic (amide)	Voltage-gated sodium channels
Digital nerve block with bupivacaine	Digital nerve block with bupivacaine	Tehran University of Medical Sciences	marketed	Local anesthetic	Voltage-gated sodium channels
Propofol, Lidocaine and fentanyl	Propofol, Lidocaine and fentanyl	Kasr El Aini Hospital	marketed	Anesthetic combination (sedative-hypnotic, local anesthetic, opioid)	GABA-A receptor (propofol), voltage-gated sodium channels (lidocaine), mu-opioid receptor (fentanyl)
Standard dose zonisamide	Standard dose zonisamide	Mario Negri Institute for Pharmacological Research	marketed	Sulfonamide anticonvulsant	Voltage-gated sodium channels, T-type calcium channels, GABA signaling
Lidocaine per-embolization	Lidocaine per-embolization	University Health Network, Toronto	marketed	Local anesthetic	Voltage-gated sodium channels
Topical Lidocaine	Topical Lidocaine	Aultman Health Foundation	marketed	Local anesthetic	Voltage-gated sodium channels
Hyperbaric Levobupivacaine 0.75%	Hyperbaric Levobupivacaine 0.75%	Fundacion Clinica Valle del Lili	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide) class)

1. Poznan University of Medical Sciences · 4 drugs in this class
2. Nantes University Hospital · 3 drugs in this class
3. Bozyaka Training and Research Hospital · 2 drugs in this class
4. ASST Gaetano Pini-CTO · 2 drugs in this class
5. Centre Hospitalier Universitaire de Nīmes · 1 drug in this class
6. Chiang Mai University · 1 drug in this class
7. Beijing Tiantan Hospital · 1 drug in this class
8. Complejo Hospitalario Universitario de Granada · 1 drug in this class
9. Ciusss de L'Est de l'Île de Montréal · 1 drug in this class
10. China Medical University, China · 1 drug in this class