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Propofol/Lidocaine — Competitive Intelligence Brief

Propofol/Lidocaine (Propofol/Lidocaine) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Intravenous anesthetic combination. Area: Anesthesiology.

marketed Intravenous anesthetic combination GABA-A receptor (propofol); voltage-gated sodium channels (lidocaine) Anesthesiology Small molecule Live · refreshed every 30 min

Target snapshot

Propofol/Lidocaine (Propofol/Lidocaine) — NYU Langone Health. Propofol and lidocaine together provide rapid induction and maintenance of anesthesia with reduced pain on injection through synergistic central nervous system depression.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Propofol/Lidocaine TARGET Propofol/Lidocaine NYU Langone Health marketed Intravenous anesthetic combination GABA-A receptor (propofol); voltage-gated sodium channels (lidocaine)
ketamine and propofol ketamine and propofol Ain Shams University marketed Intravenous anesthetic combination NMDA receptor (ketamine); GABA-A receptor (propofol)
Propofol and Alfentanil Propofol and Alfentanil North District Hospital marketed Intravenous anesthetic combination (hypnotic + opioid) GABA-A receptor (propofol); mu opioid receptor (alfentanil)
Sedation Etomidate combined with propofol Sedation Etomidate combined with propofol RenJi Hospital marketed Intravenous anesthetic combination GABA-A receptor
Propofol + Alfentanil Propofol + Alfentanil Region Jönköping County marketed Intravenous anesthetic combination (hypnotic + opioid) GABA-A receptor (propofol); mu-opioid receptor (alfentanil)
Propofol + Remifentanyl Propofol + Remifentanyl Azienda Ospedaliera San Gerardo di Monza phase 3 Intravenous anesthetic combination (hypnotic + opioid) GABA-A receptor (propofol); mu-opioid receptor (remifentanil)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Intravenous anesthetic combination class)

  1. Ain Shams University · 1 drug in this class
  2. NYU Langone Health · 1 drug in this class
  3. RenJi Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Propofol/Lidocaine — Competitive Intelligence Brief. https://druglandscape.com/ci/propofol-lidocaine. Accessed 2026-05-16.

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