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Propofol/Lidocaine — Competitive Intelligence Brief
marketed
Intravenous anesthetic combination
GABA-A receptor (propofol); voltage-gated sodium channels (lidocaine)
Anesthesiology
Small molecule
Live · refreshed every 30 min
Target snapshot
Propofol/Lidocaine (Propofol/Lidocaine) — NYU Langone Health. Propofol and lidocaine together provide rapid induction and maintenance of anesthesia with reduced pain on injection through synergistic central nervous system depression.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Propofol/Lidocaine TARGET | Propofol/Lidocaine | NYU Langone Health | marketed | Intravenous anesthetic combination | GABA-A receptor (propofol); voltage-gated sodium channels (lidocaine) | |
| ketamine and propofol | ketamine and propofol | Ain Shams University | marketed | Intravenous anesthetic combination | NMDA receptor (ketamine); GABA-A receptor (propofol) | |
| Propofol and Alfentanil | Propofol and Alfentanil | North District Hospital | marketed | Intravenous anesthetic combination (hypnotic + opioid) | GABA-A receptor (propofol); mu opioid receptor (alfentanil) | |
| Sedation Etomidate combined with propofol | Sedation Etomidate combined with propofol | RenJi Hospital | marketed | Intravenous anesthetic combination | GABA-A receptor | |
| Propofol + Alfentanil | Propofol + Alfentanil | Region Jönköping County | marketed | Intravenous anesthetic combination (hypnotic + opioid) | GABA-A receptor (propofol); mu-opioid receptor (alfentanil) | |
| Propofol + Remifentanyl | Propofol + Remifentanyl | Azienda Ospedaliera San Gerardo di Monza | phase 3 | Intravenous anesthetic combination (hypnotic + opioid) | GABA-A receptor (propofol); mu-opioid receptor (remifentanil) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Intravenous anesthetic combination class)
- Ain Shams University · 1 drug in this class
- NYU Langone Health · 1 drug in this class
- RenJi Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Propofol/Lidocaine — Competitive Intelligence Brief. https://druglandscape.com/ci/propofol-lidocaine. Accessed 2026-05-16.
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