PIB 0.2% ropivacaine — Competitive Intelligence Brief

PIB 0.2% ropivacaine (PIB 0.2% ropivacaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide class). Area: Anesthesia.

marketed Local anesthetic (amide class) Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

PIB 0.2% ropivacaine (PIB 0.2% ropivacaine) — University Health Network, Toronto. Ropivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
PIB 0.2% ropivacaine TARGET	PIB 0.2% ropivacaine	University Health Network, Toronto	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Levobupivacaine without epinephrine	Levobupivacaine without epinephrine	Pontificia Universidad Catolica de Chile	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
bupivacaine 0.25 % injection	bupivacaine 0.25 % injection	Ain Shams University	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Bupivacaine 0.167%	Bupivacaine 0.167%	Bozyaka Training and Research Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Intravenous Lidocaine	Intravenous Lidocaine	Khon Kaen University	marketed	Local anesthetic; antiarrhythmic agent	Voltage-gated sodium channels
Bupivacaine (Hyperbaric 0.5%)	Bupivacaine (Hyperbaric 0.5%)	Guy's and St Thomas' NHS Foundation Trust	marketed	Local anesthetic	Voltage-gated sodium channels
Paravertebral block using local anesthetic	Paravertebral block using local anesthetic	University of Wisconsin, Madison	marketed	Local anesthetic regional nerve block	Voltage-gated sodium channels (non-selective)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide class) class)

1. Ain Shams University · 2 drugs in this class
2. Başakşehir Çam & Sakura City Hospital · 2 drugs in this class
3. TriHealth Inc. · 2 drugs in this class
4. Centre of Postgraduate Medical Education · 2 drugs in this class
5. Bozyaka Training and Research Hospital · 2 drugs in this class
6. Complejo Hospitalario Universitario de Granada · 1 drug in this class
7. Clinique Saint-Jean, Bruxelles · 1 drug in this class
8. Hospital Clínico Universitario de Valencia · 1 drug in this class
9. Fundacion Clinica Valle del Lili · 1 drug in this class
10. Federal University of Minas Gerais · 1 drug in this class