optimized ibuprofen — Competitive Intelligence Brief

optimized ibuprofen (optimized ibuprofen) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Nonsteroidal anti-inflammatory drug (NSAID). Area: Pain Management, Inflammation.

marketed Nonsteroidal anti-inflammatory drug (NSAID) COX-1, COX-2 Pain Management, Inflammation Small molecule

Target snapshot

optimized ibuprofen (optimized ibuprofen) — OSF Healthcare System. Ibuprofen inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation, pain, and fever.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
optimized ibuprofen TARGET	optimized ibuprofen	OSF Healthcare System	marketed	Nonsteroidal anti-inflammatory drug (NSAID)	COX-1, COX-2
Naproxen Sodium + Codeine Phosphate	Naproxen Sodium + Codeine Phosphate	ibrahim doğru	marketed	NSAID + opioid analgesic combination	COX-1, COX-2, mu-opioid receptor
Paracetamol + ibuprofen	Paracetamol + ibuprofen	Ullevaal University Hospital	marketed	Analgesic/antipyretic combination	COX-1, COX-2 (ibuprofen); prostaglandin synthesis pathway (paracetamol)
Aspirin, Acetaminophen, Caffeine pills	Aspirin, Acetaminophen, Caffeine pills	Albert Einstein Healthcare Network	marketed	Analgesic combination product	Cyclooxygenase (COX-1, COX-2); adenosine receptors (caffeine)
NSAID (Aceclofenac)	NSAID (Aceclofenac)	Dong-A ST Co., Ltd.	marketed	NSAID (nonsteroidal anti-inflammatory drug)	COX-1, COX-2
Standard Dose Ibuprofen	Standard Dose Ibuprofen	Ottawa Hospital Research Institute	marketed	Nonsteroidal anti-inflammatory drug (NSAID)	COX-1, COX-2
Acular LS	Acular LS	University of Colorado, Denver	marketed	Topical NSAID	COX-1, COX-2

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Nonsteroidal anti-inflammatory drug (NSAID) class)

1. Università degli Studi di Brescia · 4 drugs in this class
2. Bausch & Lomb Incorporated · 4 drugs in this class
3. Bayer · 3 drugs in this class
4. Pfizer · 3 drugs in this class
5. Azienda USL Reggio Emilia - IRCCS · 3 drugs in this class
6. Organon and Co · 3 drugs in this class
7. Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division · 2 drugs in this class
8. Bezmialem Vakif University · 2 drugs in this class
9. Guang'anmen Hospital of China Academy of Chinese Medical Sciences · 2 drugs in this class
10. Center For Excellence In Eye Care · 2 drugs in this class