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OnabotulinumtoxinA 100 UNT [Botox] — Competitive Intelligence Brief
marketed
Neurotoxin; botulinum toxin type A
SNAP-25 (synaptosome-associated protein of 25 kDa)
Neurology; Dermatology; Aesthetics
Small molecule
Live · refreshed every 30 min
Target snapshot
OnabotulinumtoxinA 100 UNT [Botox] (OnabotulinumtoxinA 100 UNT [Botox]) — Women and Infants Hospital of Rhode Island. OnabotulinumtoxinA blocks the release of acetylcholine at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| OnabotulinumtoxinA 100 UNT [Botox] TARGET | OnabotulinumtoxinA 100 UNT [Botox] | Women and Infants Hospital of Rhode Island | marketed | Neurotoxin; botulinum toxin type A | SNAP-25 (synaptosome-associated protein of 25 kDa) | |
| Botulinum toxin A "Botox Cosmetics" | Botulinum toxin A "Botox Cosmetics" | Croma-Pharma GmbH | marketed | Neurotoxin; acetylcholine release inhibitor | SNARE complex (synaptosome-associated protein); acetylcholine release machinery | |
| Botox infiltration | Botox infiltration | University Rovira i Virgili | marketed | Neurotoxin; botulinum toxin type A | SNARE complex (synaptosome-associated protein); acetylcholine release machinery | |
| BOTULINUM TOXIN TYPE B | BOTULINUM TOXIN TYPE B | Eisai Co., Ltd. | marketed | Neurotoxin; botulinum toxin | Synaptobrevin (VAMP) | |
| powder BoNT-A (BOTOX/Vistabel) | powder BoNT-A (BOTOX/Vistabel) | Galderma R&D | marketed | Neurotoxin; botulinum toxin type A | SNAP-25 (synaptosome-associated protein of 25 kDa) | |
| Onabotulinumtoxin A (BoNT) | Onabotulinumtoxin A (BoNT) | Edgar LeClaire, MD | marketed | Neurotoxin; botulinum toxin serotype A | SNAP-25 (synaptosome-associated protein of 25 kDa) | |
| Botulinum Toxin-A injection | Botulinum Toxin-A injection | Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust | marketed | Neurotoxin; neuromuscular blocking agent | SNARE complex (specifically cleaves SNAP-25) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Neurotoxin; botulinum toxin type A class)
- Galderma R&D · 1 drug in this class
- The Methodist Hospital Research Institute · 1 drug in this class
- University Hospital, Clermont-Ferrand · 1 drug in this class
- University Rovira i Virgili · 1 drug in this class
- Women and Infants Hospital of Rhode Island · 1 drug in this class
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Cite this brief
Drug Landscape (2026). OnabotulinumtoxinA 100 UNT [Botox] — Competitive Intelligence Brief. https://druglandscape.com/ci/onabotulinumtoxina-100-unt-botox. Accessed 2026-05-17.
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