Local administration of ropivacaine — Competitive Intelligence Brief

Local administration of ropivacaine (Local administration of ropivacaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide). Area: Anesthesia / Pain Management.

phase 3 Local anesthetic (amide) Voltage-gated sodium channels Anesthesia / Pain Management Small molecule

Target snapshot

Local administration of ropivacaine (Local administration of ropivacaine) — Centre Hospitalier Universitaire de Nīmes. Ropivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials to produce local anesthesia.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Local administration of ropivacaine TARGET	Local administration of ropivacaine	Centre Hospitalier Universitaire de Nīmes	phase 3	Local anesthetic (amide)	Voltage-gated sodium channels
Transdermal Lidocaine Patch	Transdermal Lidocaine Patch	University of Wisconsin, Madison	marketed	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine 0.5% + epinephrin 1/200000	Levobupivacaine 0.5% + epinephrin 1/200000	University Hospital, Antwerp	marketed	Local anesthetic with vasoconstrictor	Voltage-gated sodium channels; alpha-adrenergic receptors
SUP Lidocaine	SUP Lidocaine	University of Michigan	marketed	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine 0,5%	Levobupivacaine 0,5%	ASST Gaetano Pini-CTO	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Liposome bupivacaine	Liposome bupivacaine	Catherine Vandepitte, M.D.	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
Intravenous Lidocaine infusion + Standard Anesthesia	Intravenous Lidocaine infusion + Standard Anesthesia	Instituto Mexicano del Seguro Social	marketed	Local anesthetic (sodium channel blocker)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide) class)

1. Poznan University of Medical Sciences · 4 drugs in this class
2. Nantes University Hospital · 3 drugs in this class
3. Bozyaka Training and Research Hospital · 2 drugs in this class
4. ASST Gaetano Pini-CTO · 2 drugs in this class
5. Centre Hospitalier Universitaire de Nīmes · 1 drug in this class
6. Chiang Mai University · 1 drug in this class
7. Beijing Tiantan Hospital · 1 drug in this class
8. Complejo Hospitalario Universitario de Granada · 1 drug in this class
9. Ciusss de L'Est de l'Île de Montréal · 1 drug in this class
10. China Medical University, China · 1 drug in this class