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SUP Lidocaine
SUP Lidocaine is a topical formulation of lidocaine, a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission.
SUP Lidocaine is a topical formulation of lidocaine, a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission. Used for Localized pain relief (specific indication dependent on SUP formulation type).
At a glance
| Generic name | SUP Lidocaine |
|---|---|
| Also known as | Generic lidocaine (Henry Schein Inc) |
| Sponsor | University of Michigan |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Pain management / Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Lidocaine works by inhibiting the influx of sodium ions through voltage-gated sodium channels in nerve fibers, thereby preventing depolarization and blocking the generation and conduction of action potentials. This results in local anesthesia at the site of application. The SUP formulation (likely a suppository or specialized delivery system) allows for localized pain relief in specific anatomical regions.
Approved indications
- Localized pain relief (specific indication dependent on SUP formulation type)
Common side effects
- Local irritation or burning at application site
- Allergic contact dermatitis
- Systemic toxicity (if absorbed in large quantities)
Key clinical trials
- Superior Hypogastric Nerve Block for Pain Control Post-uterine Fibroid Embolization (PHASE2)
- Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- SUP Lidocaine CI brief — competitive landscape report
- SUP Lidocaine updates RSS · CI watch RSS
- University of Michigan portfolio CI