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Local administration of ropivacaine

Centre Hospitalier Universitaire de Nīmes · Phase 3 active Small molecule

Local administration of ropivacaine is a Local anesthetic (amide) Small molecule drug developed by Centre Hospitalier Universitaire de Nīmes. It is currently in Phase 3 development for Local anesthesia for surgical and medical procedures, Postoperative pain management via local infiltration.

Ropivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials to produce local anesthesia.

Ropivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials to produce local anesthesia. Used for Local anesthesia for surgical and medical procedures, Postoperative pain management via local infiltration.

At a glance

Generic nameLocal administration of ropivacaine
SponsorCentre Hospitalier Universitaire de Nīmes
Drug classLocal anesthetic (amide)
TargetVoltage-gated sodium channels
ModalitySmall molecule
Therapeutic areaAnesthesia / Pain Management
PhasePhase 3

Mechanism of action

Ropivacaine reversibly inhibits sodium influx through voltage-gated sodium channels in nerve fibers, thereby stabilizing the neuronal membrane and preventing depolarization. This blocks the transmission of pain signals and other sensory information in the localized area of administration. The drug is an amide-type local anesthetic with a long duration of action and reduced cardiotoxicity compared to some other local anesthetics.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Local administration of ropivacaine

What is Local administration of ropivacaine?

Local administration of ropivacaine is a Local anesthetic (amide) drug developed by Centre Hospitalier Universitaire de Nīmes, indicated for Local anesthesia for surgical and medical procedures, Postoperative pain management via local infiltration.

How does Local administration of ropivacaine work?

Ropivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials to produce local anesthesia.

What is Local administration of ropivacaine used for?

Local administration of ropivacaine is indicated for Local anesthesia for surgical and medical procedures, Postoperative pain management via local infiltration.

Who makes Local administration of ropivacaine?

Local administration of ropivacaine is developed by Centre Hospitalier Universitaire de Nīmes (see full Centre Hospitalier Universitaire de Nīmes pipeline at /company/centre-hospitalier-universitaire-de-n-mes).

What drug class is Local administration of ropivacaine in?

Local administration of ropivacaine belongs to the Local anesthetic (amide) class. See all Local anesthetic (amide) drugs at /class/local-anesthetic-amide.

What development phase is Local administration of ropivacaine in?

Local administration of ropivacaine is in Phase 3.

What are the side effects of Local administration of ropivacaine?

Common side effects of Local administration of ropivacaine include Injection site reactions, Transient neurological symptoms, Systemic toxicity (at high doses), Allergic reactions.

What does Local administration of ropivacaine target?

Local administration of ropivacaine targets Voltage-gated sodium channels and is a Local anesthetic (amide).

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