Liposomal bupivacaine left injection — Competitive Intelligence Brief

Liposomal bupivacaine left injection (Liposomal bupivacaine left injection) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide). Area: Anesthesia / Pain Management.

marketed Local anesthetic (amide) Voltage-gated sodium channels Anesthesia / Pain Management Small molecule

Target snapshot

Liposomal bupivacaine left injection (Liposomal bupivacaine left injection) — Prisma Health-Upstate. Liposomal bupivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses to produce local anesthesia.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Liposomal bupivacaine left injection TARGET	Liposomal bupivacaine left injection	Prisma Health-Upstate	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
intravenous saline plus perineural bupivacaine	intravenous saline plus perineural bupivacaine	Sherif Mohamed Abd el moneim Soaida, MD	marketed	Local anesthetic with supportive fluid therapy	Voltage-gated sodium channels (Nav)
Depofoam bupivacaine	Depofoam bupivacaine	The Cleveland Clinic	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
Brand lamotrigine	Brand lamotrigine	University of Maryland, Baltimore	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release inhibition
Lamotrigine generic "B"	Lamotrigine generic "B"	University of Cincinnati	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release inhibition
Hyperbaric Bupivicaine	Hyperbaric Bupivicaine	University of Witwatersrand, South Africa	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Lidocaïne 2%	Lidocaïne 2%	University of Liege	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide) class)

1. Poznan University of Medical Sciences · 4 drugs in this class
2. Nantes University Hospital · 3 drugs in this class
3. Bozyaka Training and Research Hospital · 2 drugs in this class
4. ASST Gaetano Pini-CTO · 2 drugs in this class
5. Centre Hospitalier Universitaire de Nīmes · 1 drug in this class
6. Chiang Mai University · 1 drug in this class
7. Beijing Tiantan Hospital · 1 drug in this class
8. Complejo Hospitalario Universitario de Granada · 1 drug in this class
9. Ciusss de L'Est de l'Île de Montréal · 1 drug in this class
10. China Medical University, China · 1 drug in this class