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intravenous saline plus perineural bupivacaine

Sherif Mohamed Abd el moneim Soaida, MD · FDA-approved active Small molecule

intravenous saline plus perineural bupivacaine is a Local anesthetic with supportive fluid therapy Small molecule drug developed by Sherif Mohamed Abd el moneim Soaida, MD. It is currently FDA-approved for Regional anesthesia and postoperative pain management via perineural nerve blocks.

Intravenous saline provides fluid and electrolyte support while perineural bupivacaine blocks nerve conduction locally to provide regional anesthesia and analgesia.

Intravenous saline provides fluid and electrolyte support while perineural bupivacaine blocks nerve conduction locally to provide regional anesthesia and analgesia. Used for Regional anesthesia and postoperative pain management via perineural nerve blocks.

At a glance

Generic nameintravenous saline plus perineural bupivacaine
SponsorSherif Mohamed Abd el moneim Soaida, MD
Drug classLocal anesthetic with supportive fluid therapy
TargetVoltage-gated sodium channels (Nav)
ModalitySmall molecule
Therapeutic areaAnesthesia and Pain Management
PhaseFDA-approved

Mechanism of action

Bupivacaine is a local anesthetic that works by blocking sodium channels in nerve cell membranes, preventing action potential propagation and thus pain signal transmission in the targeted nerve region. When administered perineural (around a nerve), it provides regional anesthesia and postoperative analgesia. The intravenous saline component maintains fluid and electrolyte balance during the procedure.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about intravenous saline plus perineural bupivacaine

What is intravenous saline plus perineural bupivacaine?

intravenous saline plus perineural bupivacaine is a Local anesthetic with supportive fluid therapy drug developed by Sherif Mohamed Abd el moneim Soaida, MD, indicated for Regional anesthesia and postoperative pain management via perineural nerve blocks.

How does intravenous saline plus perineural bupivacaine work?

Intravenous saline provides fluid and electrolyte support while perineural bupivacaine blocks nerve conduction locally to provide regional anesthesia and analgesia.

What is intravenous saline plus perineural bupivacaine used for?

intravenous saline plus perineural bupivacaine is indicated for Regional anesthesia and postoperative pain management via perineural nerve blocks.

Who makes intravenous saline plus perineural bupivacaine?

intravenous saline plus perineural bupivacaine is developed and marketed by Sherif Mohamed Abd el moneim Soaida, MD (see full Sherif Mohamed Abd el moneim Soaida, MD pipeline at /company/sherif-mohamed-abd-el-moneim-soaida-md).

What drug class is intravenous saline plus perineural bupivacaine in?

intravenous saline plus perineural bupivacaine belongs to the Local anesthetic with supportive fluid therapy class. See all Local anesthetic with supportive fluid therapy drugs at /class/local-anesthetic-with-supportive-fluid-therapy.

What development phase is intravenous saline plus perineural bupivacaine in?

intravenous saline plus perineural bupivacaine is FDA-approved (marketed).

What are the side effects of intravenous saline plus perineural bupivacaine?

Common side effects of intravenous saline plus perineural bupivacaine include Systemic toxicity (CNS and cardiac effects), Local tissue irritation or nerve injury, Hypotension, Bradycardia.

What does intravenous saline plus perineural bupivacaine target?

intravenous saline plus perineural bupivacaine targets Voltage-gated sodium channels (Nav) and is a Local anesthetic with supportive fluid therapy.

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