Last reviewed · How we verify
intravenous sedation with propofol — Competitive Intelligence Brief
phase 3
GABA_A receptor agonist
GABA_A receptor
Anesthesiology
Small molecule
Live · refreshed every 30 min
Target snapshot
intravenous sedation with propofol (intravenous sedation with propofol) — University Hospital, Clermont-Ferrand. Propofol acts as a GABA_A receptor agonist, enhancing the inhibitory effects of GABA in the brain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| intravenous sedation with propofol TARGET | intravenous sedation with propofol | University Hospital, Clermont-Ferrand | phase 3 | GABA_A receptor agonist | GABA_A receptor | |
| Propofol induced sedation | Propofol induced sedation | Centre Hospitalier Universitaire de Saint Etienne | phase 3 | GABA_A receptor agonist | GABA_A receptor | |
| Remifentanil and/or propofol | Remifentanil and/or propofol | Alder Hey Children's NHS Foundation Trust | phase 3 | Opioid analgesic, Sedative-hypnotic | Opioid receptors, GABA_A receptor | |
| treatments for essential tremor | treatments for essential tremor | US Department of Veterans Affairs | phase 3 | GABA_A receptor modulator | GABA_A receptor | |
| Stiripentol Oral Capsule | Stiripentol Oral Capsule | Biocodex | phase 3 | GABA_A receptor modulator | GABA_A receptor | |
| The midazolam ketamine group | The midazolam ketamine group | Kasr El Aini Hospital | phase 3 | Benzodiazepine and NMDA receptor antagonist | GABA_A receptor, NMDA receptor | |
| Sevoflurane, Sufentanil | Sevoflurane, Sufentanil | University of Saskatchewan | phase 3 | General anesthetic, Opioid analgesic | GABA_A receptor, Mu-opioid receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GABA_A receptor agonist class)
- Alkermes, Inc. · 1 drug in this class
- Assistance Publique - Hôpitaux de Paris · 1 drug in this class
- Centre Hospitalier Universitaire de Saint Etienne · 1 drug in this class
- The Cleveland Clinic · 1 drug in this class
- University Hospital, Clermont-Ferrand · 1 drug in this class
- Xiaobo Yang, MD · 1 drug in this class
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Cite this brief
Drug Landscape (2026). intravenous sedation with propofol — Competitive Intelligence Brief. https://druglandscape.com/ci/intravenous-sedation-with-propofol. Accessed 2026-05-16.
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