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intravenous sedation with propofol — Competitive Intelligence Brief

intravenous sedation with propofol (intravenous sedation with propofol) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: GABA_A receptor agonist. Area: Anesthesiology.

phase 3 GABA_A receptor agonist GABA_A receptor Anesthesiology Small molecule Live · refreshed every 30 min

Target snapshot

intravenous sedation with propofol (intravenous sedation with propofol) — University Hospital, Clermont-Ferrand. Propofol acts as a GABA_A receptor agonist, enhancing the inhibitory effects of GABA in the brain.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
intravenous sedation with propofol TARGET intravenous sedation with propofol University Hospital, Clermont-Ferrand phase 3 GABA_A receptor agonist GABA_A receptor
Propofol induced sedation Propofol induced sedation Centre Hospitalier Universitaire de Saint Etienne phase 3 GABA_A receptor agonist GABA_A receptor
Remifentanil and/or propofol Remifentanil and/or propofol Alder Hey Children's NHS Foundation Trust phase 3 Opioid analgesic, Sedative-hypnotic Opioid receptors, GABA_A receptor
treatments for essential tremor treatments for essential tremor US Department of Veterans Affairs phase 3 GABA_A receptor modulator GABA_A receptor
Stiripentol Oral Capsule Stiripentol Oral Capsule Biocodex phase 3 GABA_A receptor modulator GABA_A receptor
The midazolam ketamine group The midazolam ketamine group Kasr El Aini Hospital phase 3 Benzodiazepine and NMDA receptor antagonist GABA_A receptor, NMDA receptor
Sevoflurane, Sufentanil Sevoflurane, Sufentanil University of Saskatchewan phase 3 General anesthetic, Opioid analgesic GABA_A receptor, Mu-opioid receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (GABA_A receptor agonist class)

  1. Alkermes, Inc. · 1 drug in this class
  2. Assistance Publique - Hôpitaux de Paris · 1 drug in this class
  3. Centre Hospitalier Universitaire de Saint Etienne · 1 drug in this class
  4. The Cleveland Clinic · 1 drug in this class
  5. University Hospital, Clermont-Ferrand · 1 drug in this class
  6. Xiaobo Yang, MD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). intravenous sedation with propofol — Competitive Intelligence Brief. https://druglandscape.com/ci/intravenous-sedation-with-propofol. Accessed 2026-05-16.

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