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treatments for essential tremor
This drug targets the GABA_A receptor to modulate neuronal excitability.
This drug targets the GABA_A receptor to modulate neuronal excitability. Used for Essential tremor.
At a glance
| Generic name | treatments for essential tremor |
|---|---|
| Sponsor | US Department of Veterans Affairs |
| Drug class | GABA_A receptor modulator |
| Target | GABA_A receptor |
| Modality | Small molecule |
| Therapeutic area | Neurology |
| Phase | Phase 3 |
Mechanism of action
By enhancing GABAergic transmission, it reduces neuronal hyperexcitability and tremor severity. This is achieved through the drug's action on the GABA_A receptor, a key component of the inhibitory neurotransmission system.
Approved indications
- Essential tremor
Common side effects
- Dizziness
- Headache
- Nausea
Key clinical trials
- EMBRACE Tremor BiFUS (NA)
- Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders (NA)
- Evaluating the Efficacy of Voice Therapy for Neurogenic Voice Disorders (NA)
- Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET)
- RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's Disease (NA)
- ET Stigma Response to Tremor Suppression
- LIFUS For Neurological Disorders (NA)
- Dual Lead Thalamic Deep Brain Recording (DBR)-DBS Interface for Closed Loop Control of Severe Essential Tremor (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- treatments for essential tremor CI brief — competitive landscape report
- treatments for essential tremor updates RSS · CI watch RSS
- US Department of Veterans Affairs portfolio CI