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Extended Phenytoin Sodium — Competitive Intelligence Brief
marketed
Aromatic antiepileptic drug (hydantoin)
Voltage-gated sodium channels
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Extended Phenytoin Sodium (Extended Phenytoin Sodium) — Bristol-Myers Squibb. Extended-release phenytoin sodium blocks voltage-gated sodium channels in the brain to reduce neuronal excitability and prevent seizure propagation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Extended Phenytoin Sodium TARGET | Extended Phenytoin Sodium | Bristol-Myers Squibb | marketed | Aromatic antiepileptic drug (hydantoin) | Voltage-gated sodium channels | |
| Control (bupivacaine) | Control (bupivacaine) | Kasr El Aini Hospital | marketed | Local anesthetic (amide) | Voltage-gated sodium channels | |
| Remifentanil+Lidocaine | Remifentanil+Lidocaine | The First Affiliated Hospital of Zhengzhou University | marketed | Opioid analgesic + Local anesthetic combination | Mu-opioid receptor (remifentanil); Voltage-gated sodium channels (lidocaine) | |
| Bupivacaine-fentanyl elective group | Bupivacaine-fentanyl elective group | Conrad Arnfinn Bjørshol | marketed | Local anesthetic with opioid analgesic combination | Voltage-gated sodium channels (bupivacaine); mu opioid receptor (fentanyl) | |
| Exparel/bupivacaine mixture | Exparel/bupivacaine mixture | Wake Forest University Health Sciences | marketed | Local anesthetic (liposomal formulation) | Voltage-gated sodium channels | |
| ropivacaine and ketorolac | ropivacaine and ketorolac | University of Aarhus | marketed | Local anesthetic + NSAID combination | Voltage-gated sodium channels (ropivacaine); COX-1 and COX-2 (ketorolac) | |
| Propofol/Lidocaine | Propofol/Lidocaine | NYU Langone Health | marketed | Intravenous anesthetic combination | GABA-A receptor (propofol); voltage-gated sodium channels (lidocaine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Aromatic antiepileptic drug (hydantoin) class)
- Bristol-Myers Squibb · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Extended Phenytoin Sodium — Competitive Intelligence Brief. https://druglandscape.com/ci/extended-phenytoin-sodium. Accessed 2026-05-16.
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