Chlorhexidine oral care — Competitive Intelligence Brief

Chlorhexidine oral care (Chlorhexidine oral care) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimicrobial agent / Antiseptic. Area: Oral Health / Dentistry.

marketed Antimicrobial agent / Antiseptic Bacterial cell membrane and proteins Oral Health / Dentistry Small molecule

Target snapshot

Chlorhexidine oral care (Chlorhexidine oral care) — University of Pavia. Chlorhexidine is an antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, providing broad-spectrum antimicrobial activity for oral care.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Chlorhexidine oral care TARGET	Chlorhexidine oral care	University of Pavia	marketed	Antimicrobial agent / Antiseptic	Bacterial cell membrane and proteins
Adapalene/Benzoyl Peroxide Gel 0.3-2.5%	Adapalene/Benzoyl Peroxide Gel 0.3-2.5%	Derm Research, PLLC	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
Adapalene/benzoyl peroxide gel, 0.1%/2.5%	Adapalene/benzoyl peroxide gel, 0.1%/2.5%	Galderma R&D	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
adapalene/benzoyl peroxide	adapalene/benzoyl peroxide	Galderma R&D	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
chlorhexidine digluconate	chlorhexidine digluconate	Universidade Federal do Ceara	marketed	Antimicrobial agent / Antiseptic	Bacterial cell membrane and proteins
Intranasal Mupirocin and Topical Chlorhexidine	Intranasal Mupirocin and Topical Chlorhexidine	University of Maryland, Baltimore	marketed	Topical antibiotic combination	Bacterial isoleucyl-tRNA synthetase (mupirocin); bacterial cell membrane and proteins (chlorhexidine)
Chlorhexidine 0.06% mouthrinse	Chlorhexidine 0.06% mouthrinse	University of Oslo	marketed	Antimicrobial oral rinse	Bacterial cell membrane and proteins

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimicrobial agent / Antiseptic class)

1. Universidad de Guanajuato · 2 drugs in this class
2. University of Oslo · 2 drugs in this class
3. Johns Hopkins University · 1 drug in this class
4. The Cooper Health System · 1 drug in this class
5. Universidade Federal do Ceara · 1 drug in this class
6. University of Milan · 1 drug in this class
7. University of Pavia · 1 drug in this class
8. University of Pennsylvania · 1 drug in this class
9. University of Santiago de Compostela · 1 drug in this class
10. HaEmek Medical Center, Israel · 1 drug in this class