Chlorhexidine 0.06% mouthrinse — Competitive Intelligence Brief

Chlorhexidine 0.06% mouthrinse (Chlorhexidine 0.06% mouthrinse) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimicrobial oral rinse. Area: Oral health / Dentistry.

marketed Antimicrobial oral rinse Bacterial cell membrane and proteins Oral health / Dentistry Small molecule

Target snapshot

Chlorhexidine 0.06% mouthrinse (Chlorhexidine 0.06% mouthrinse) — University of Oslo. Chlorhexidine is a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, reducing oral microbial load.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Chlorhexidine 0.06% mouthrinse TARGET	Chlorhexidine 0.06% mouthrinse	University of Oslo	marketed	Antimicrobial oral rinse	Bacterial cell membrane and proteins
adapalene/benzoyl peroxide	adapalene/benzoyl peroxide	Galderma R&D	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
Intranasal Mupirocin and Topical Chlorhexidine	Intranasal Mupirocin and Topical Chlorhexidine	University of Maryland, Baltimore	marketed	Topical antibiotic combination	Bacterial isoleucyl-tRNA synthetase (mupirocin); bacterial cell membrane and proteins (chlorhexidine)
Adapalene/Benzoyl Peroxide Gel 0.3-2.5%	Adapalene/Benzoyl Peroxide Gel 0.3-2.5%	Derm Research, PLLC	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
Adapalene + benzoyl peroxide samples	Adapalene + benzoyl peroxide samples	Wake Forest University	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
Lavasept 0.04%	Lavasept 0.04%	B. Braun Ltd. Centre of Excellence Infection Control	marketed	Antimicrobial antiseptic	Bacterial cell membrane and proteins
chlorhexidine digluconate	chlorhexidine digluconate	Universidade Federal do Ceara	marketed	Antimicrobial agent / Antiseptic	Bacterial cell membrane and proteins

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimicrobial oral rinse class)

1. GlaxoSmithKline · 1 drug in this class
2. Johnson & Johnson Consumer Inc. (J&JCI) · 1 drug in this class
3. Rowpar Pharmaceuticals, Inc. · 1 drug in this class
4. Universidade Estadual Paulista Júlio de Mesquita Filho · 1 drug in this class
5. University of Oslo · 1 drug in this class