Bupivacaine Spinal 0,5% Heavy - bolus — Competitive Intelligence Brief

Bupivacaine Spinal 0,5% Heavy - bolus (Bupivacaine Spinal 0,5% Heavy - bolus) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide class). Area: Anesthesiology.

marketed Local anesthetic (amide class) Voltage-gated sodium channels Anesthesiology Small molecule

Target snapshot

Bupivacaine Spinal 0,5% Heavy - bolus (Bupivacaine Spinal 0,5% Heavy - bolus) — Centre of Postgraduate Medical Education. Bupivacaine blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce local anesthesia.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine Spinal 0,5% Heavy - bolus TARGET	Bupivacaine Spinal 0,5% Heavy - bolus	Centre of Postgraduate Medical Education	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Levobupivacaine epidural bolus	Levobupivacaine epidural bolus	University of Genova	marketed	Local anesthetic (amino amide)	Voltage-gated sodium channels
Generic lamotrigine	Generic lamotrigine	University of Maryland, Baltimore	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release inhibition
Lacosamide - rapid titration 2	Lacosamide - rapid titration 2	Seoul National University Hospital	marketed	Anticonvulsant; sodium channel modulator	Voltage-gated sodium channels; CRMP-2
Carbamazepine-Implant	Carbamazepine-Implant	University of Sao Paulo	marketed	Anticonvulsant / Antiepileptic agent	Voltage-gated sodium channels
Prilocaine (Hyperbaric 2%)	Prilocaine (Hyperbaric 2%)	Guy's and St Thomas' NHS Foundation Trust	marketed	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine PCA group	Levobupivacaine PCA group	Osijek University Hospital	marketed	Local anesthetic (amide)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide class) class)

1. Ain Shams University · 2 drugs in this class
2. Başakşehir Çam & Sakura City Hospital · 2 drugs in this class
3. TriHealth Inc. · 2 drugs in this class
4. Centre of Postgraduate Medical Education · 2 drugs in this class
5. Bozyaka Training and Research Hospital · 2 drugs in this class
6. Complejo Hospitalario Universitario de Granada · 1 drug in this class
7. Clinique Saint-Jean, Bruxelles · 1 drug in this class
8. Hospital Clínico Universitario de Valencia · 1 drug in this class
9. Fundacion Clinica Valle del Lili · 1 drug in this class
10. Federal University of Minas Gerais · 1 drug in this class