Bupivacaine (Hyperbaric 0.5%) — Competitive Intelligence Brief

Bupivacaine (Hyperbaric 0.5%) (Bupivacaine (Hyperbaric 0.5%)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

Bupivacaine (Hyperbaric 0.5%) (Bupivacaine (Hyperbaric 0.5%)) — Guy's and St Thomas' NHS Foundation Trust. Bupivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine (Hyperbaric 0.5%) TARGET	Bupivacaine (Hyperbaric 0.5%)	Guy's and St Thomas' NHS Foundation Trust	marketed	Local anesthetic	Voltage-gated sodium channels
Oral Zonisamide Therapy	Oral Zonisamide Therapy	Affiliated Hospital of Nantong University	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase
oral suzetrigine	oral suzetrigine	University of Louisville	marketed	Selective sodium channel blocker	Voltage-gated sodium channels (Nav)
Bupivacaine 20cc	Bupivacaine 20cc	Hospital for Special Surgery, New York	marketed	Local anesthetic	Voltage-gated sodium channels
Bupivacaine and Fentanyl	Bupivacaine and Fentanyl	Bnai Zion Medical Center	marketed	Local anesthetic with opioid analgesic combination	Voltage-gated sodium channels (bupivacaine); mu-opioid receptor (fentanyl)
Bupivacaine Digital Block	Bupivacaine Digital Block	University of California, San Francisco	marketed	Local anesthetic	Voltage-gated sodium channels
Bupivacaine Hcl 0.5% Inj	Bupivacaine Hcl 0.5% Inj	Hospital for Special Surgery Florida	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class