Bupivacain (preoperative) — Competitive Intelligence Brief

Bupivacain (preoperative) (Bupivacain (preoperative)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide class). Area: Anesthesiology.

phase 3 Local anesthetic (amide class) Voltage-gated sodium channels Anesthesiology Small molecule

Target snapshot

Bupivacain (preoperative) (Bupivacain (preoperative)) — Başakşehir Çam & Sakura City Hospital. Bupivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacain (preoperative) TARGET	Bupivacain (preoperative)	Başakşehir Çam & Sakura City Hospital	phase 3	Local anesthetic (amide class)	Voltage-gated sodium channels
Lidocaine aerosol 2.4% topical	Lidocaine aerosol 2.4% topical	Jiangang Song	marketed	Local anesthetic	Voltage-gated sodium channels
Anesthesia (Lidocaine 15%)	Anesthesia (Lidocaine 15%)	Lumbini Medical College	marketed	Local anesthetic	Voltage-gated sodium channels
bucain + fentanyl	bucain + fentanyl	University of Debrecen	marketed	Local anesthetic + opioid analgesic combination	Voltage-gated sodium channels (bucain); mu-opioid receptor (fentanyl)
TAP block with Bupivacaine at 0.25%	TAP block with Bupivacaine at 0.25%	Patricia Salazar Villegas	marketed	Local anesthetic	Voltage-gated sodium channels
blind injection of Mepivacaine	blind injection of Mepivacaine	Complejo Hospitalario Universitario de Granada	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
lidocaine + epinephrine 1:100,000	lidocaine + epinephrine 1:100,000	Weill Medical College of Cornell University	marketed	Local anesthetic with vasoconstrictor	Voltage-gated sodium channels (lidocaine); alpha-1 and beta-1 adrenergic receptors (epinephrine)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide class) class)

1. Ain Shams University · 2 drugs in this class
2. Başakşehir Çam & Sakura City Hospital · 2 drugs in this class
3. TriHealth Inc. · 2 drugs in this class
4. Centre of Postgraduate Medical Education · 2 drugs in this class
5. Bozyaka Training and Research Hospital · 2 drugs in this class
6. Complejo Hospitalario Universitario de Granada · 1 drug in this class
7. Clinique Saint-Jean, Bruxelles · 1 drug in this class
8. Hospital Clínico Universitario de Valencia · 1 drug in this class
9. Fundacion Clinica Valle del Lili · 1 drug in this class
10. Federal University of Minas Gerais · 1 drug in this class