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blind injection of Mepivacaine
blind injection of Mepivacaine is a Local anesthetic (amide class) Small molecule drug developed by Complejo Hospitalario Universitario de Granada. It is currently FDA-approved for Local and regional anesthesia for surgical and dental procedures, Pain relief during minor medical procedures.
Mepivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of nerve impulses.
Mepivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of nerve impulses. Used for Local and regional anesthesia for surgical and dental procedures, Pain relief during minor medical procedures.
At a glance
| Generic name | blind injection of Mepivacaine |
|---|---|
| Sponsor | Complejo Hospitalario Universitario de Granada |
| Drug class | Local anesthetic (amide class) |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia / Pain Management |
| Phase | FDA-approved |
Mechanism of action
Mepivacaine reversibly inhibits sodium influx into nerve fibers, which stabilizes the neuronal membrane and prevents depolarization. This action blocks conduction of sensory, motor, and autonomic nerve impulses in the area where it is injected. The 'blind injection' technique refers to administration without direct visualization of the target nerve or tissue.
Approved indications
- Local and regional anesthesia for surgical and dental procedures
- Pain relief during minor medical procedures
Common side effects
- Injection site reactions (pain, erythema)
- Transient paresthesia
- Systemic toxicity (CNS effects, cardiac arrhythmias) with overdose
- Allergic reactions
Key clinical trials
- Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients (NA)
- Photobiomodulation for Controlling Pre-Local Anesthetic Injection Pain (NA)
- Plantar Compartment Block Versus Sciatic Block in Hallux Valgus Ambulatory Surgery (NA)
- Comparative Evaluation of Pulpal Anaesthetic Efficacy of Different Anaesthetic Solutions for Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis (NA)
- The Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Lower Jaw Dental Injections (PHASE4)
- Blind and Ultrasound Guided Injection in Morton Neuroma (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- blind injection of Mepivacaine CI brief — competitive landscape report
- blind injection of Mepivacaine updates RSS · CI watch RSS
- Complejo Hospitalario Universitario de Granada portfolio CI
Frequently asked questions about blind injection of Mepivacaine
What is blind injection of Mepivacaine?
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Related
- Drug class: All Local anesthetic (amide class) drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Complejo Hospitalario Universitario de Granada — full pipeline
- Therapeutic area: All drugs in Anesthesia / Pain Management
- Indication: Drugs for Local and regional anesthesia for surgical and dental procedures
- Indication: Drugs for Pain relief during minor medical procedures
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