Who are Bifonazole spray twice daily's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Ketoconazole 2% Shampoo, medium itraconazole tablet, Clotrimazole vaginal tablets+ Lactobacillus, Loceryl NL 12 weeks, clotrimazole vaginal tablets, Bifonazole Cream.

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Last reviewed 2026-05-16 · How we verify

Bifonazole spray twice daily — Competitive Intelligence Brief

Bifonazole spray twice daily (Bifonazole spray twice daily) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Triazole antifungal. Area: Dermatology.

phase 2 Triazole antifungal Lanosterol 14α-demethylase Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Bifonazole spray twice daily (Bifonazole spray twice daily) — Bayer. Bifonazole is an antifungal agent that works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Bifonazole spray twice daily TARGET	Bifonazole spray twice daily	Bayer	phase 2	Triazole antifungal	Lanosterol 14α-demethylase
Ketoconazole 2% Shampoo	Ketoconazole 2% Shampoo	Fakultas Kedokteran Universitas Indonesia	marketed	Imidazole antifungal	Fungal cytochrome P450 (CYP51 / lanosterol 14α-demethylase)
medium itraconazole tablet	medium itraconazole tablet	University of Maryland, Baltimore	marketed	Triazole antifungal	Fungal CYP51 (lanosterol 14α-demethylase)
Clotrimazole vaginal tablets+ Lactobacillus	Clotrimazole vaginal tablets+ Lactobacillus	Peking University Shenzhen Hospital	marketed	Antifungal + probiotic combination	Fungal lanosterol 14α-demethylase (CYP51); Lactobacillus competitive exclusion and microbiota restoration
Loceryl NL 12 weeks	Loceryl NL 12 weeks	Galderma R&D	marketed	Allylamine antifungal	Lanosterol 14α-demethylase (CYP51)
clotrimazole vaginal tablets	clotrimazole vaginal tablets	Peking University Shenzhen Hospital	marketed	Imidazole antifungal	Lanosterol 14α-demethylase (CYP51)
Bifonazole Cream	Bifonazole Cream	Galderma R&D	marketed	Imidazole antifungal	Lanosterol 14α-demethylase (CYP51)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Triazole antifungal class)

University of Maryland, Baltimore · 3 drugs in this class
Manjunath Prakash Pai · 2 drugs in this class
Pfizer · 2 drugs in this class
Janssen Pharmaceutical K.K. · 1 drug in this class
Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
Merck Sharp & Dohme LLC · 1 drug in this class
Seoul National University Hospital · 1 drug in this class
University of California, San Francisco · 1 drug in this class
University of Minnesota · 1 drug in this class
Bayer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Bifonazole spray twice daily — Competitive Intelligence Brief. https://druglandscape.com/ci/bifonazole-spray-twice-daily. Accessed 2026-05-16.

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