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BCI-540 — Competitive Intelligence Brief
phase 2
GABA_A receptor modulator
GABA_A receptor
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
BCI-540 (BCI-540) — BrainCells Inc.. BCI-540 is a small molecule that modulates the activity of GABA_A receptors.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| BCI-540 TARGET | BCI-540 | BrainCells Inc. | phase 2 | GABA_A receptor modulator | GABA_A receptor | |
| Sevoflurane, Sufentanil | Sevoflurane, Sufentanil | University of Saskatchewan | phase 3 | General anesthetic, Opioid analgesic | GABA_A receptor, Mu-opioid receptor | |
| Remifentanil and/or propofol | Remifentanil and/or propofol | Alder Hey Children's NHS Foundation Trust | phase 3 | Opioid analgesic, Sedative-hypnotic | Opioid receptors, GABA_A receptor | |
| Propofol-Lipuro | Propofol-Lipuro | University Hospital, Grenoble | phase 3 | GABA receptor agonist | GABA_A receptor | |
| Propofol induced sedation | Propofol induced sedation | Centre Hospitalier Universitaire de Saint Etienne | phase 3 | GABA_A receptor agonist | GABA_A receptor | |
| SAGE-547 | SAGE-547 | Supernus Pharmaceuticals, Inc. | phase 3 | antisense oligonucleotide | GABA_A receptor alpha 1 subunit | |
| Sevoflurane intravenous anesthesia | Sevoflurane intravenous anesthesia | The Cleveland Clinic | phase 3 | Volatile anesthetic | GABA_A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GABA_A receptor modulator class)
- Biocodex · 1 drug in this class
- BrainCells Inc. · 1 drug in this class
- US Department of Veterans Affairs · 1 drug in this class
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Cite this brief
Drug Landscape (2026). BCI-540 — Competitive Intelligence Brief. https://druglandscape.com/ci/bci-540. Accessed 2026-05-14.
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