Who are Atarax (Hydroxyzine)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Benadryl demand, Ciclesonide & Levocetirizine, Diphenhydramine 5%, Azelastine - intranasal application, Antihistamine Cetirizine Hydrochloride, Olopatadine Nasal Spray.

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Last reviewed 2026-05-13 · How we verify

Atarax (Hydroxyzine) — Competitive Intelligence Brief

Atarax (Hydroxyzine) (Atarax (Hydroxyzine)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: First-generation H1 antihistamine. Area: Psychiatry / Dermatology / Allergy.

marketed First-generation H1 antihistamine H1 histamine receptor Psychiatry / Dermatology / Allergy Small molecule Live · refreshed every 30 min

Target snapshot

Atarax (Hydroxyzine) (Atarax (Hydroxyzine)) — University Hospital, Toulouse. Hydroxyzine is a first-generation antihistamine that blocks H1 receptors to reduce histamine-mediated allergic and anxiety responses.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Atarax (Hydroxyzine) TARGET	Atarax (Hydroxyzine)	University Hospital, Toulouse	marketed	First-generation H1 antihistamine	H1 histamine receptor
Benadryl demand	Benadryl demand	University of Pennsylvania	marketed	First-generation H1 antihistamine	H1 histamine receptor
Ciclesonide & Levocetirizine	Ciclesonide & Levocetirizine	Handok Inc.	marketed	Inhaled corticosteroid + selective H1-receptor antagonist combination	Glucocorticoid receptor (ciclesonide); H1 histamine receptor (levocetirizine)
Diphenhydramine 5%	Diphenhydramine 5%	Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology	marketed	H1 receptor antagonist (first-generation antihistamine)	H1 histamine receptor
Azelastine - intranasal application	Azelastine - intranasal application	Association Asthma, Bulgaria	marketed	Selective H1-receptor antagonist (intranasal antihistamine)	H1 histamine receptor
Antihistamine Cetirizine Hydrochloride	Antihistamine Cetirizine Hydrochloride	Goldman, Butterwick, Fitzpatrick and Groff	marketed	H1-receptor antagonist (second-generation antihistamine)	H1 histamine receptor
Olopatadine Nasal Spray	Olopatadine Nasal Spray	ORA, Inc.	marketed	Selective H1-receptor antagonist / mast cell stabilizer	H1 histamine receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (First-generation H1 antihistamine class)

National Cancer Institute (NCI) · 1 drug in this class
University Hospital, Toulouse · 1 drug in this class
University of Pennsylvania · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Atarax (Hydroxyzine) — Competitive Intelligence Brief. https://druglandscape.com/ci/atarax-hydroxyzine. Accessed 2026-05-13.

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