alkalinized lidocaine — Competitive Intelligence Brief

alkalinized lidocaine (alkalinized lidocaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia/Pain Management.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia/Pain Management Small molecule

Target snapshot

alkalinized lidocaine (alkalinized lidocaine) — Massachusetts General Hospital. Alkalinized lidocaine is a local anesthetic that blocks sodium channels in nerve cell membranes, with alkalinization enhancing its tissue penetration and onset speed.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
alkalinized lidocaine TARGET	alkalinized lidocaine	Massachusetts General Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine and sodium bicarbonate	Lidocaine and sodium bicarbonate	University of Zurich	marketed	Local anesthetic	Voltage-gated sodium channels
LIDOCAINE 1 %	LIDOCAINE 1 %	Ain Shams Maternity Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Mepivacaine Injection	Mepivacaine Injection	Nova Scotia Health Authority	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
lignocaine+bicarbonate	lignocaine+bicarbonate	Aligarh Muslim University	marketed	Local anesthetic	Voltage-gated sodium channels
Lidoderm 5% patch	Lidoderm 5% patch	Nicole K Brogden	marketed	Local anesthetic	Voltage-gated sodium channels
liposomal bupivacaine local infiltration	liposomal bupivacaine local infiltration	Second Affiliated Hospital, School of Medicine, Zhejiang University	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class