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NCT07139756: HYPOPARK
Deciphering the Mechanisms of Central BP Regulation in Patients With PD Associated With Orthostatic Hypotension
trial testing Lower body negative pressure in Parkinson Disease in 130 participants. Not yet recruiting.
30 September 2027
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire Vaudois |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 130 |
| Start date | 1 October 2025 |
| Primary completion | 30 September 2027 |
| Estimated completion | 31 March 2028 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Lower body negative pressure
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
- Orthostatic Hypotension — all drugs for Orthostatic Hypotension →
Sponsor
Centre Hospitalier Universitaire Vaudois
Who can join
Adults 18 to 75, any sex, with Parkinson Disease or Orthostatic Hypotension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Phase 1 objective: test the feasibility of using a 3Tesla MRI scanner instead of a 7Tesla MRI scanner to measure brainstem responses to LBNP in healthy participants. Phase 2 primary objective: compare the brainstem responses to LBNP in patients with PD associated with OH to PD patients without OH using BOLD fMRI
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07139756
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Parkinson Disease
Currently open trials in the same condition.
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Other Centre Hospitalier Universitaire Vaudois trials
Trials by the same sponsor.
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- NCT07268378 — Supervision of Clinicians in Oncology by Psycho-oncologists : Evaluation · NA · enrolling by invitation
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07139756 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire Vaudois
- Last refreshed: 24 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07139756.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing