Last reviewed · How we verify
NCT05705115: Volu-Flow
Acetated Ringer´s Solution in Experimental Hypovolemia
Phase 4 trial testing Ringer acetate in Hypovolemia in 12 participants. Status unknown.
29 July 2024
Quick facts
| Lead sponsor | Oslo University Hospital |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 12 |
| Start date | 2 March 2024 |
| Primary completion | 29 July 2024 |
| Estimated completion | 29 July 2024 |
| Sites | 1 location across Norway |
Drugs / interventions tested
- Ringer acetate
- Lower body negative pressure
Conditions studied
- Hypovolemia — all drugs for Hypovolemia →
- Fluid Loss — all drugs for Fluid Loss →
- Hemodynamic Instability — all drugs for Hemodynamic Instability →
Sponsor
Oslo University Hospital
Who can join
Adults 18 to 40, any sex, with Hypovolemia or Fluid Loss. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Intravenous fluids are often given to increase stroke volume and thereby improve global oxygen delivery. The effect is however often transient, but the effect of a fluid bolus on stroke volume and other hemodynamic variables over time are poorly described. The volume effect of a fluid bolus (effect on blood volume) can be calculated by measuring Haemoglobin. The purpose of this study is to elucidate the hemodynamic effects of a fluid bolus during normovolemia and hypovolemia in healthy volunteers. Study details include: • Study Duration: 2 visits of approximately 2 h duration each + follow-up visit. Visits 1 and 2 are at least 2 days apart. Number of Participants: A maximum of 15 participants will be enrolled to study intervention such that 12 evaluable participants complete the study
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05705115
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05705115 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oslo University Hospital
- Last refreshed: 5 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05705115.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing