Last reviewed · How we verify
NCT05464927: VMP
Visualizing Vascular Mechanisms of Lipedema
trial in Lipedema in 110 participants. Participants enrolled and being followed up; not accepting new ones.
1 January 2027
Quick facts
| Lead sponsor | University of Virginia |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 110 |
| Start date | 1 September 2021 |
| Primary completion | 1 January 2027 |
| Estimated completion | 1 January 2027 |
| Sites | 1 location across United States |
Conditions studied
- Lipedema — all drugs for Lipedema →
Sponsor
University of Virginia
Who can join
Adults 18 to 80, female only, with Lipedema. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This work will address clinical unmet needs for patients with lipedema using advanced magnetic resonance imaging (MRI) methods, in sequence with portable clinical tools, by testing fundamental hypotheses regarding potential screening methods, lymphatic therapy, and vascular dysfunction in patients with lipedema.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Lipedema: Insights into Morphology, Pathophysiology, and Challenges.
Poojari A, Dev K, Rabiee A. · · 2022 · cited 47× · PMID 36551837 · DOI 10.3390/biomedicines10123081 -
Vascular changes and their implications in lipedema.
Al-Ghadban S, Guo Y, Juskiewicz ZJ, Crescenzi R, et al · · 2026 · PMID 42181679 · DOI 10.3389/fcell.2026.1819443
Verify or expand the search:
- PubMed search for NCT05464927
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lipedema
Currently open trials in the same condition.
- NCT07489248 — Multimodal Ultrasound for Differentiating Lymphedema and Lipedema · recruiting
- NCT07468097 — The Impact of Metabolic Status on Pain and Central Sensitization in Women With Lipedema: A Cross-Sectional Observational · recruiting
- NCT07294014 — Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema · recruiting
- NCT07458932 — Evaluation of Physical Activity in Women With Lipedema · recruiting
- NCT06558851 — The Effect of Systematic Endurance Training in Treatment of Women With Lipedema · NA · active not recruiting
Other University of Virginia trials
Trials by the same sponsor.
- NCT05880355 — Multimodality Cardiovascular Imaging for the Translation of Therapies for Vascular Activation After MI · EARLY_PHASE1 · not yet recruiting
- NCT07405645 — Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy · NA · recruiting
- NCT07146685 — Effect of Local Anesthetic Concentration on Rebound Pain: A Randomized Control Study · Phase 4 · not yet recruiting
- NCT07298941 — Resilience Enhancement Following Sleep Treatment · Phase 2 · recruiting
- NCT07036315 — Meaning in Music-Based Pain Modulation · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05464927 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Virginia
- Last refreshed: 27 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05464927.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing