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NCT05211050: SLIM
Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine
NA trial testing Levcromakalim in Migraine Without Aura in 24 participants. Completed in 5 November 2023.
5 November 2023
Quick facts
| Lead sponsor | Danish Headache Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | quadruple |
| Primary purpose | other |
| Enrollment | 24 |
| Start date | 15 March 2022 |
| Primary completion | 5 November 2023 |
| Estimated completion | 5 November 2023 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Levcromakalim — full drug profile →
- Sumatriptan (SUMATRIPTAN) — full drug profile →
- Saline
Conditions studied
- Migraine Without Aura — all drugs for Migraine Without Aura →
- Headache — all drugs for Headache →
Sponsor
Danish Headache Center — full company profile →
Who can join
Adults 18 to 65, any sex, with Migraine Without Aura or Headache. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aims to explore the effects of Sumatriptan on Levcromakalim-induced migraine in individuals with migraine without aura.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05211050
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Levcromakalim
Trials testing the same drug.
- NCT05889442 — Effect of Levcromakalim in Individuals With Migraine Pretreated With Erenumab · NA · completed
- NCT05565001 — The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain. · NA · unknown
- NCT05243953 — Hypersensitivity to Opening of ATP-Sensitive Potassium Channels in Post-Traumatic Headache · NA · completed
- NCT04905654 — Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura · NA · completed
- NCT05093582 — The Effects of Levcromakalim in Patients With Cluster Headache · NA · completed
Other recruiting trials for Migraine Without Aura
Currently open trials in the same condition.
- NCT05889624 — Responding With Evidence and Access for Childhood Headaches · NA · recruiting
- NCT05903027 — Gepant treAtments: EffectIveNess and tolERability (GAINER) · recruiting
- NCT05484349 — TIzanidine for the Preventive Treatment of Episodic MigrainE （TIME） · Phase 3 · recruiting
- NCT04715685 — Mind Body Balance for Pediatric Migraine · NA · recruiting
Other Danish Headache Center trials
Trials by the same sponsor.
- NCT07451769 — Selective Activation of the Adrenomedullin Receptors in Migraine · NA · not yet recruiting
- NCT07342296 — Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activating Polypeptide-38 · NA · not yet recruiting
- NCT07059546 — Hypersensitivity to Adrenomedullin in Post-Traumatic Headache · NA · recruiting
- NCT07021859 — Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide · NA · recruiting
- NCT06959004 — Substance P-Induced Migraine Attacks Without Aura · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05211050 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Danish Headache Center
- Last refreshed: 22 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05211050.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing