NCT07451769 is a NA clinical trial of Adrenomedullin in Migraine, sponsored by Danish Headache Center.

Who is sponsoring NCT07451769?

NCT07451769 is sponsored by Danish Headache Center.

What drugs are being tested in NCT07451769?

Interventions in NCT07451769: Adrenomedullin, Placebo.

What condition does NCT07451769 study?

NCT07451769 studies Migraine, Brain Diseases, Central Nervous System Diseases, Adrenomedullin, Pain, Peptides, Neuropeptides, Signs and Symptoms.

Is NCT07451769 still recruiting?

NCT07451769 is currently not yet recruiting. Last updated 9 March 2026.

Last reviewed 2026-03-09 · How we verify

NCT07451769

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Selective Activation of the Adrenomedullin Receptors in Migraine

Not yet recruiting NA Last updated 9 March 2026

What this trial tests

NA trial testing Adrenomedullin in Migraine in 26 participants. Not yet recruiting.

Timeline

10 March 2026

Primary endpoint
10 March 2027

20 December 2032

Quick facts

Lead sponsor	Danish Headache Center
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	basic science
Enrollment	26
Start date	10 March 2026
Primary completion	10 March 2027
Estimated completion	20 December 2032
Sites	1 location across Denmark

Drugs / interventions tested

Adrenomedullin — full drug profile →
Placebo

Conditions studied

Migraine — all drugs for Migraine →
Brain Diseases — all drugs for Brain Diseases →
Central Nervous System Diseases — all drugs for Central Nervous System Diseases →
Adrenomedullin — all drugs for Adrenomedullin →

Sponsor

Danish Headache Center — full company profile →

Who can join

Adults 18 to 65, any sex, with Migraine or Brain Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Adrenomedullin is a neuropeptide implicated in the pathogenesis of migraine. This study investigates whether its administration, after pre-treatment with erenumab (a CGRP-receptor blocking monoclonal antibody), can trigger migraine attacks in individuals with migraine without aura.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Adrenomedullin

Trials testing the same drug.

NCT07059546 — Hypersensitivity to Adrenomedullin in Post-Traumatic Headache · NA · recruiting
NCT06072118 — Adrenomedullin for CADASIL · Phase 2 · completed
NCT04111484 — Adrenomedullin Effect on Migraine Without Patients · NA · completed

Other recruiting trials for Migraine

Currently open trials in the same condition.

NCT07419607 — MIGRAFIT: Evaluating a Group Therapy Program Combining Physical Activity, Progressive Muscle Relaxation and Psychoeducat · NA · recruiting
NCT07487701 — Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study · NA · active not recruiting
NCT07343427 — Impact of GON PRF on Central Sensitization in Migraine Patients · NA · active not recruiting
NCT07336056 — Nerivio Efficacy Under High-Frequency Use · Phase 4 · active not recruiting
NCT07385755 — Desvenlafaxine for Preventive Treatment of Frequent Migraines · NA · active not recruiting

Other Danish Headache Center trials

Trials by the same sponsor.

NCT07342296 — Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activating Polypeptide-38 · NA · not yet recruiting
NCT07059546 — Hypersensitivity to Adrenomedullin in Post-Traumatic Headache · NA · recruiting
NCT07021859 — Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide · NA · recruiting
NCT06959004 — Substance P-Induced Migraine Attacks Without Aura · NA · recruiting
NCT06859463 — Muscle Function and Tenderness Differences in Headache Patients · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07451769 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Danish Headache Center
Last refreshed: 9 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07451769.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing