NCT04771923 (TAVA) is a NA clinical trial of Tranexamic acid in Bleeding, sponsored by Clinical Hospital Centre Zagreb.

Who is sponsoring NCT04771923?

NCT04771923 is sponsored by Clinical Hospital Centre Zagreb.

What drugs are being tested in NCT04771923?

Interventions in NCT04771923: Tranexamic acid, Adrenaline.

What condition does NCT04771923 study?

NCT04771923 studies Bleeding, Hemoptysis.

Is NCT04771923 still recruiting?

NCT04771923 is currently completed. Last updated 24 February 2022.

Last reviewed 2022-02-24 · How we verify

NCT04771923: TAVA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Tranexamic Acid Versus Adrenaline for Controlling Iatrogenic Endobronchial Bleeding

Completed NA Last updated 24 February 2022

What this trial tests

NA trial testing Tranexamic acid in Bleeding in 130 participants. Completed in 4 February 2022.

Timeline

22 February 2021

Primary endpoint
4 February 2022

4 February 2022

Quick facts

Lead sponsor	Clinical Hospital Centre Zagreb
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	130
Start date	22 February 2021
Primary completion	4 February 2022
Estimated completion	4 February 2022
Sites	1 location across Croatia

Drugs / interventions tested

Tranexamic acid (Tranexamic Acid) — full drug profile →
Adrenaline — full drug profile →

Conditions studied

Bleeding — all drugs for Bleeding →
Hemoptysis — all drugs for Hemoptysis →

Sponsor

Clinical Hospital Centre Zagreb

Who can join

18 and older, any sex, with Bleeding or Hemoptysis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Endobronchial bleeding is a relatively common complication of diagnostic bronchoscopy. Both tranexamic acid and adrenaline are used topically for the control of endobronchial bleeding. The aim of this study is to compare the efficacy of tranexamic acid with adrenaline in controlling iatrogenic endobronchial bleeding after diagnostic bronchoscopy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Tranexamic Acid vs Adrenaline for Controlling Iatrogenic Bleeding During Flexible Bronchoscopy: A Double-Blind Randomized Controlled Trial.
Badovinac S, Glodić G, Sabol I, Džubur F, et al · · 2023 · cited 9× · PMID 36273651 · DOI 10.1016/j.chest.2022.10.013

Verify or expand the search:

Other trials of Tranexamic acid

Trials testing the same drug.

NCT07278037 — Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage · recruiting
NCT06599762 — Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia · Phase 2 · recruiting
NCT06657924 — Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery · Phase 2 · recruiting
NCT06806241 — Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery · recruiting
NCT06419075 — Tranexamic Acid in Vaginal Reconstructive Surgery · Phase 4 · withdrawn

Other recruiting trials for Bleeding

Currently open trials in the same condition.

NCT07401394 — BAR-TAX - Tranexamic Acid in Bariatric Surgery. · NA · active not recruiting
NCT07309848 — Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs · recruiting
NCT07083583 — Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders · recruiting
NCT07019077 — Incidence of Late Haemorrhage After Invasive Gastroenterological Endoscopic Manoeuvre in Patients Treated With Anticoagu · recruiting
NCT07358416 — Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery. · active not recruiting

Other Clinical Hospital Centre Zagreb trials

Trials by the same sponsor.

NCT07456111 — A Comparison of Remimazolam Besylate and Propofol Sedation in Patients Undergoing Colonoscopic Polypectomy · Phase 4 · recruiting
NCT07131800 — Objective and Perceptual Characteristics of the Voice After Endotracheal Intubation in Head and Neck Surgery · enrolling by invitation
NCT06145191 — Prophylactic Tranexamic Acid Versus Adrenaline During Flexible Bronchoscopy · NA · completed
NCT06144398 — Single Use Flexible Bronchoscopes in Interventional Pulmonary Procedures · NA · completed
NCT05741736 — Five Days for Health (FDH): Small Group-based Lifestyle Modification Program on Weight Loss · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04771923 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Clinical Hospital Centre Zagreb
Last refreshed: 24 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04771923.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing