Last reviewed · How we verify
NCT07309848: OPTIMIZEDOAC
Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs
trial in Blood Transfusion in 374 participants. Currently enrolling.
1 September 2027
Quick facts
| Lead sponsor | St. Antonius Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 374 |
| Start date | 1 November 2025 |
| Primary completion | 1 September 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 7 locations across Netherlands |
Conditions studied
- Blood Transfusion — all drugs for Blood Transfusion →
- Hip Fracture Surgeries — all drugs for Hip Fracture Surgeries →
- Geriatric — all drugs for Geriatric →
- Bleeding Complications — all drugs for Bleeding Complications →
Sponsor
St. Antonius Hospital
Who can join
Eligibility, any sex, with Blood Transfusion or Hip Fracture Surgeries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study looks at patients with hip fractures who are taking direct oral anticoagulants (DOACs), a type of blood thinner. In many hospitals, surgery for these patients is delayed because of concerns about bleeding, but waiting longer can also increase risks such as complications and longer hospital stays. The purpose of this study is to find out whether operating within 24 hours is as safe as delaying surgery beyond 24 hours. Specifically, the investigators want to know if early surgery does not lead to a higher need for blood transfusions compared to delayed surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07309848
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other St. Antonius Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07309848 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. Antonius Hospital
- Last refreshed: 30 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07309848.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing