Who is sponsoring NCT04283643?

NCT04283643 is sponsored by University of Virginia.

What drugs are being tested in NCT04283643?

Interventions in NCT04283643: Transcranial Focused Ultrasound, Transcranial Magnetic Stimulation.

What condition does NCT04283643 study?

NCT04283643 studies Pain, Acute, Pain, Chronic, Pain, Experimental.

Is NCT04283643 still recruiting?

NCT04283643 is currently status unknown. Last updated 25 February 2020.

Last reviewed 2020-02-25 · How we verify

NCT04283643

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Noninvasive Brain Stimulation for Pain Relief

Status unknown NA Last updated 25 February 2020

What this trial tests

NA trial testing Transcranial Focused Ultrasound in Pain, Acute in 149 participants. Status unknown.

Timeline

1 April 2019

Primary endpoint
1 April 2021

1 April 2021

Quick facts

Lead sponsor	University of Virginia
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	149
Start date	1 April 2019
Primary completion	1 April 2021
Estimated completion	1 April 2021
Sites	1 location across United States

Drugs / interventions tested

Transcranial Focused Ultrasound
Transcranial Magnetic Stimulation — full drug profile →

Conditions studied

Pain, Acute — all drugs for Pain, Acute →
Pain, Chronic — all drugs for Pain, Chronic →
Pain, Experimental — all drugs for Pain, Experimental →

Sponsor

University of Virginia

Who can join

Adults 18 to 80, any sex, with Pain, Acute or Pain, Chronic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Non-invasive brain stimulation techniques, transcranial magnetic stimulation (TMS) and transcranial focused ultrasound (FUS), is be applied to healthy human subjects, acute pain patients, and chronic pain patients to investigate their uses for pain relief.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Magnetic Resonance-guided Focused Ultrasound thalamotomy for refractory neuropathic pain: a systematic review and critical appraisal of current knowledge.
Taranta V, Saporito G, Ornello R, Splendiani A, et al · · 2023 · cited 7× · PMID 37363184 · DOI 10.1177/17562864231180729

Verify or expand the search:

Other trials of Transcranial Focused Ultrasound

Trials testing the same drug.

NCT06461221 — tFUS to Enhance Alertness and Performance · EARLY_PHASE1 · withdrawn
NCT06718140 — tFUS for Memory in mNCD and Healthy Adults · Phase 1 · enrolling by invitation
NCT05895474 — Safety Assessment of Central Medial Thalamus Stimulation Using Transcranial Focused Ultrasound · NA · completed

Other recruiting trials for Pain, Acute

Currently open trials in the same condition.

NCT07249827 — A Randomized Comparison Between 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg of Perineural Dexmedetomidine for Ultrasound-Guid · Phase 2 · recruiting
NCT07053774 — Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain · Phase 2 · recruiting
NCT07009951 — Impact of Virtual Reality in Cardiac Electrophysiology · recruiting
NCT06960317 — Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements · NA · recruiting
NCT06754657 — CORA-Q15: Continuous vs. Single-injection Interscalene Block on QoR-15 in Outpatient Rotator Cuff Surgery · Phase 4 · recruiting

Other University of Virginia trials

Trials by the same sponsor.

NCT05880355 — Multimodality Cardiovascular Imaging for the Translation of Therapies for Vascular Activation After MI · EARLY_PHASE1 · not yet recruiting
NCT07405645 — Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy · NA · recruiting
NCT07146685 — Effect of Local Anesthetic Concentration on Rebound Pain: A Randomized Control Study · Phase 4 · not yet recruiting
NCT07298941 — Resilience Enhancement Following Sleep Treatment · Phase 2 · recruiting
NCT07036315 — Meaning in Music-Based Pain Modulation · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04283643 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Virginia
Last refreshed: 25 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04283643.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing