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NCT04124276
Evaluation of Efficacy of Lycium Barbarum Polysaccharide in Patients With Major Depressive Disorder
NA trial testing Lycium barbarum polysaccharide in Major Depressive Disorder in 284 participants. Status unknown.
30 December 2020
Quick facts
| Lead sponsor | Guangzhou Psychiatric Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 284 |
| Start date | 1 November 2019 |
| Primary completion | 30 December 2020 |
| Estimated completion | 1 June 2021 |
| Sites | 1 location across China |
Drugs / interventions tested
- Lycium barbarum polysaccharide
- Placebo
Conditions studied
- Major Depressive Disorder — all drugs for Major Depressive Disorder →
- Depression — all drugs for Depression →
- Depressive Disorder — all drugs for Depressive Disorder →
Sponsor
Guangzhou Psychiatric Hospital
Who can join
Adults 18 to 60, any sex, with Major Depressive Disorder or Depression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lycium barbarum, a traditional Chinese herbal medicine, is a commonly used herb in the traditional Chinese pharmacopoeia. Its main active ingredient, lycium barbarum polysaccharide (LBP), is reported to have neuroprotective effects. Animal studies suggested that LBP has neuroprotective effect on optic ganglion cells. In animal models of depression, LBP can improve depressive symptom by improving synaptic plasticity. However, its clinical effect remains to be studied. We will conduct a 6-week double-blind, randomized, placebo-con-trolled trial in patients with major depressive disorder (MDD). The purpose of this clinical trial is to investigate the efficacy of LBP in patients with MDD.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04124276
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
Other trials of Lycium barbarum polysaccharide
Trials testing the same drug.
- NCT04032795 — Evaluation of Efficacy of Lycium Barbarum Polysaccharide in People With Subthreshold Depression · NA · unknown
Other recruiting trials for Major Depressive Disorder
Currently open trials in the same condition.
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- NCT06705478 — Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disor · Phase 2 · recruiting
- NCT06749392 — An Individual-specific Synchrony Signature · NA · recruiting
- NCT07316803 — Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness · NA · recruiting
- NCT07242105 — Optimizing Brain Excitability in Depression · NA · recruiting
Other Guangzhou Psychiatric Hospital trials
Trials by the same sponsor.
- NCT06658795 — Treating Loneliness In The Older Adult With Depression With tDCS · NA · recruiting
- NCT04816617 — The Effect of Exercise on Cognition and Preventing Depression in Young People · NA · completed
- NCT04803071 — Omega-3 Unsaturated Fatty Acid Improves Cognitive Function in Patients With Depression · NA · unknown
- NCT04447430 — Light Therapy to Improve Symptoms in Pregnant Women With Major Depressive Disorder · NA · unknown
- NCT04032795 — Evaluation of Efficacy of Lycium Barbarum Polysaccharide in People With Subthreshold Depression · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04124276 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Guangzhou Psychiatric Hospital
- Last refreshed: 30 October 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04124276.
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