NCT01770067 is a NA clinical trial of CITA-RNPT in Infection, sponsored by Hillel Yaffe Medical Center.

Who is sponsoring NCT01770067?

NCT01770067 is sponsored by Hillel Yaffe Medical Center.

What drugs are being tested in NCT01770067?

Interventions in NCT01770067: CITA-RNPT, Extraction of infected CIED.

Is NCT01770067 still recruiting?

NCT01770067 is currently status unknown. Last updated 26 January 2022.

Last reviewed 2022-01-26 · How we verify

NCT01770067

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prospective Evaluation of the Efficacy and Safety of Continuous In-situ Ultra High-dose Antibiotics (CITA) and Minimally Invasive Surgery (MIS) Utilizing Regulated Negative Pressure-assisted Wound Therapy (RNPT) in the Salvage of Infected Cardiovascular Implantable Electronic Devices (CIED) by Localized High-dose Antibiotics

Status unknown NA Last updated 26 January 2022

What this trial tests

NA trial testing CITA-RNPT in Infection in 100 participants. Status unknown.

Timeline

1 February 2013

Primary endpoint
1 February 2023

1 February 2023

Quick facts

Lead sponsor	Hillel Yaffe Medical Center
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	non randomized
Design	single group
Masking	none
Primary purpose	prevention
Enrollment	100
Start date	1 February 2013
Primary completion	1 February 2023
Estimated completion	1 February 2023
Sites	1 location across Israel

Drugs / interventions tested

CITA-RNPT — full drug profile →
Extraction of infected CIED

Conditions studied

Infection — all drugs for Infection →

Sponsor

Hillel Yaffe Medical Center

Who can join

15 and older, any sex, with Infection. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Lack of CIED Infection
Time frame: One year

Sponsor's own description

Following previous positive experience with regulated CITA-RNPT of infected CIEDs, we suggest increasing the number of recruited patients and that CITA-RNPT can be administered prophylactically to patients prior to replacement of previously treated CIEDs, immuno-compromised patients, and others.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Negative pressure wound therapy for surgical wounds healing by primary closure.
Webster J, Liu Z, Norman G, Dumville JC, et al · · 2019 · cited 73× · PMID 30912582 · DOI 10.1002/14651858.cd009261.pub4
Negative pressure wound therapy for surgical wounds healing by primary closure.
Norman G, Shi C, Goh EL, Murphy EM, et al · · 2022 · cited 71× · PMID 35471497 · DOI 10.1002/14651858.cd009261.pub7
Negative pressure wound therapy for surgical wounds healing by primary closure.
Norman G, Goh EL, Dumville JC, Shi C, et al · · 2020 · cited 48× · PMID 32542647 · DOI 10.1002/14651858.cd009261.pub6
Negative pressure wound therapy for surgical wounds healing by primary closure.
Norman G, Goh EL, Dumville JC, Shi C, et al · · 2020 · cited 38× · PMID 32356396 · DOI 10.1002/14651858.cd009261.pub5
Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections.
Topaz M, Chorin E, Schwartz AL, Hochstadt A, et al · · 2023 · cited 26× · PMID 36631206 · DOI 10.1016/j.jacc.2022.10.022

Verify or expand the search:

Other recruiting trials for Infection

Currently open trials in the same condition.

NCT07358117 — Viral Infections of the Central Nervous System: Diagnosis and Clinical Outcome · active not recruiting
NCT07110636 — Microbial Cell-free Metagenomic Sequencing for Suspected Infections in Adult Immunocompromised Outpatients · NA · recruiting
NCT06806709 — Reducing Blood Culture Contamination With the Use of a Needle-less Blood Draw Device (The PIVO Trial) · NA · recruiting
NCT06974162 — Metagenomics for Ocular Inflammation · recruiting
NCT07370948 — Study of the Antibiotic-resistance Profile of Enterobacterales Isolated From Rectal Mucosal Buffer of PrEP Subjects · recruiting

Other Hillel Yaffe Medical Center trials

Trials by the same sponsor.

NCT06643052 — Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator · not yet recruiting
NCT07134985 — Pediatric Patients Who Leave the Emergency Department Without Treatment · recruiting
NCT06927193 — Regional Analgesia at the Pediatric Emergency Department · recruiting
NCT07233525 — Home-Based Language and Cognitive Intervention for Arab Toddlers in Israel · NA · not yet recruiting
NCT07320339 — The Aim of the Study is to Examine the Variation in Blood Pressure Between an Optimal Measurement (According to Establis · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01770067 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hillel Yaffe Medical Center
Last refreshed: 26 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01770067.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing