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NCT06806709

Reducing Blood Culture Contamination With the Use of a Needle-less Blood Draw Device (The PIVO Trial)

Recruiting now NA Last updated 4 February 2026
What this trial tests

NA trial testing PIVO-Pro needle-free blood collection device in Blood Culture Contamination in 1,148 participants. Currently enrolling.

Timeline
18 August 2025
Primary endpoint
30 October 2026
31 December 2026

Quick facts

Lead sponsorThe University of Queensland
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposeother
Enrollment1,148
Start date18 August 2025
Primary completion30 October 2026
Estimated completion31 December 2026
Sites4 locations across Australia

Drugs / interventions tested

Conditions studied

Sponsor

The University of Queensland

Who can join

18 and older, any sex, with Blood Culture Contamination or Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Blood cultures (BCs) are a blood test to look for an infection. Two problems with the sample collection are contamination by germs outside of the blood and not collecting enough blood in the tube, resulting in unusable samples. Many patients requiring a BC also have a peripheral intravenous catheter ("catheter") but these are not normally used for blood sampling. This means that patients receive many painful needles for both catheter insertion and blood sampling. There is a needle-free blood collection device (PIVO Pro) which can be used with a catheter to collect a blood sample. The goal of the PIVO Trial is to see if using the PIVO Pro for blood culture sample collection will have a lower amount of contamination than the usual method of blood sample collection. Patients 18 and older at 3 emergency departments will be included. Research nurses will look for patients in emergency who need a blood culture sample taken and they will be asked if they want to be involved in the trial. Half of the participants will use the PIVO Pro to take their blood sample and half will have the usual way of collecting blood. Participants do not have to do anything specifically for the trial. Information about the blood collection and results of the blood culture will be collected from the medical records and recorded for the trial.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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