NCT06643052

Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator

Not yet recruiting Last updated 7 April 2026

What this trial tests

trial testing No intervention in Neonatal Early-onset Sepsis in 6,300 participants. Not yet recruiting.

Timeline

1 December 2026

Primary endpoint
1 June 2027

1 December 2027

Quick facts

Lead sponsor	Hillel Yaffe Medical Center
Status	Not yet recruiting
Study type	OBSERVATIONAL
Enrollment	6,300
Start date	1 December 2026
Primary completion	1 June 2027
Estimated completion	1 December 2027
Sites	1 location across Israel

Drugs / interventions tested

• No intervention

Conditions studied

• Neonatal Early-onset Sepsis — all drugs for Neonatal Early-onset Sepsis →

Sponsor

Hillel Yaffe Medical Center

Who can join

Under 7 Days, any sex, with Neonatal Early-onset Sepsis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.

The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedica l center.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.