SGLT2 — Drug Target
All drugs that target SGLT2 — marketed and clinical-stage. Includes 2 drug classes acting on this target.
Drug classes
Sodium-Glucose Cotransporter 2 Inhibitor [EPC] · SGLT2 inhibitor
Marketed (22)
- Jardiance · Boehringer Ingelheim · Sodium-Glucose Cotransporter 2 Inhibitor [EPC] · Metabolic
SYNJARDY combines empagliflozin, which inhibits SGLT2 to increase urinary glucose excretion, and metformin HCl, which improves glucose tolerance and insulin sensitivity. - North Star · Neuvosyn Laboratories, LLC · SGLT2 inhibitor · Diabetes
North Star is a small molecule that acts as a selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - FPT-20 · Trieu, Nguyen Thi, M.D. · SGLT2 inhibitor · Diabetes
FPT-20 is a selective and potent inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - xin te mie · Xiangbei Welman Pharmaceutical Co., Ltd · SGLT2 inhibitor · Diabetes
Xin te mie is a small molecule that acts as a selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - LG-group · Medical University of Vienna · SGLT2 inhibitor · Diabetes
LG-group drugs are used to treat type 2 diabetes by lowering blood sugar levels. - Maintenance treatment · RWTH Aachen University · SGLT2 inhibitor · Diabetes
This drug works by inhibiting the reabsorption of sodium in the kidneys, leading to increased excretion of sodium and water. - Concomitant therapy 14 days · Incheon St.Mary's Hospital · SGLT2 inhibitor · Diabetes
This drug is used to treat various conditions by inhibiting the reabsorption of sodium and water in the kidneys. - Brenzavvy · Theracosbio · Sodium-Glucose Cotransporter 2 Inhibitor [EPC] · Metabolic
Bexagliflozin inhibits SGLT2 to reduce renal glucose reabsorption and increase urinary glucose excretion. - Standard treatment strategy · Fundación para la Investigación del Hospital Clínico de Valencia · SGLT2 inhibitor · Diabetes
This drug works by inhibiting the reabsorption of sodium and water in the kidneys. - NBF · Universidad Complutense de Madrid · SGLT2 inhibitor · Diabetes
NBF is a selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - CTM Boost · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · SGLT2 inhibitor · Diabetes
CTM Boost is a small molecule that acts as a selective and potent inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - A1 · Breath of Life International Pharma Ltd · SGLT2 inhibitor · Diabetes
A1 works by inhibiting the action of a specific enzyme. - senfrol monotherapy · Peking University Third Hospital · SGLT2 inhibitor · Diabetes
Senfrol monotherapy works by inhibiting the activity of a specific enzyme. - Ertugliflozin 15 mg · Pfizer · SGLT2 inhibitor · Metabolic
- phase II · Suzhou Genhouse Bio Co., Ltd. · SGLT2 inhibitor · Diabetes
This drug works by inhibiting the activity of a specific enzyme. - B55R1 and B55R2 · AJU Pharm Co., Ltd. · SGLT2 inhibitor · Diabetes
B55R1 and B55R2 are inhibitors of the sodium-glucose cotransporter 2 (SGLT2). - Weight Based Group · University of Colorado, Denver · SGLT2 inhibitor · Diabetes
This drug works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys, reducing glucose reabsorption and lowering blood glucose levels. - A5 · Breath of Life International Pharma Ltd · SGLT2 inhibitor · Diabetes
A5 is a medication that works by inhibiting the action of a specific enzyme. - GnP · West China Hospital · SGLT2 inhibitor · Diabetes
GnP is a small molecule that acts as a selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - Ertugliflozin 5 mg · Pfizer · SGLT2 inhibitor · Metabolic
- Keverprazan 10 days · Second Affiliated Hospital, School of Medicine, Zhejiang University · SGLT2 inhibitor · Diabetes
Keverprazan is a selective and reversible inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - CDobi · Services Hospital, Lahore · SGLT2 inhibitor · Diabetes
CDobi is a medication that works by inhibiting the activity of a specific enzyme.
Phase 3 pipeline (178)
- PF04965842 · Pfizer · SGLT2 inhibitor · Diabetes
PF04965842 is a small molecule drug that targets the SGLT2 receptor. - V419 · Merck Sharp & Dohme LLC · SGLT2 inhibitor · Diabetes
V419 is a small molecule that targets the SGLT2 receptor. - RLD2209-1 · Hanmi Pharmaceutical Company Limited · SGLT2 inhibitor · Diabetes
RLD2209-1 is a small molecule that targets the SGLT2 receptor. - RLD2106-1 · Hanmi Pharmaceutical Company Limited · SGLT2 inhibitor · Diabetes
RLD2106-1 is a small molecule that targets the SGLT2 receptor. - Double blind control period A140 · Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. · SGLT2 inhibitor · Diabetes
A140 is a small molecule that targets the SGLT2 receptor. - GNR-067 · AO GENERIUM · SGLT2 inhibitor · Diabetes
GNR-067 is a small molecule that targets the SGLT2 receptor. - DWKH-R · Daewon Pharmaceutical Co., Ltd. · SGLT2 inhibitor · Diabetes
DWKH-R is a small molecule that targets the SGLT2 receptor. - VGA039 · Vega Therapeutics, Inc · SGLT2 inhibitor · Diabetes
VGA039 is a small molecule inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - TS-152 · Taisho Pharmaceutical Co., Ltd. · SGLT2 inhibitor · Diabetes
TS-152 is a small molecule that targets the SGLT2 receptor. - AND017 · Kind Pharmaceuticals LLC · SGLT2 inhibitor · Diabetes
AND017 is a small molecule that targets the SGLT2 receptor. - Apetiviton BC · Cifarma Cientifica Farmaceutica Ltda · SGLT2 inhibitor · Diabetes
Apetiviton BC is a drug that works by inhibiting the action of a specific enzyme. - CG5503 · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · SGLT2 inhibitor · Diabetes
CG5503 is a small molecule that targets the SGLT2 receptor. - BMI2006 · BMI Korea · SGLT2 inhibitor · Diabetes
BMI2006 is a small molecule drug that targets the SGLT2 receptor. - C2402 · JW Pharmaceutical · SGLT2 inhibitor · Diabetes
C2402 is a small molecule that targets the SGLT2 receptor. - HS627 · BioRay Pharmaceutical Co., Ltd. · SGLT2 inhibitor · Diabetes
HS627 is a small molecule that targets the SGLT2 receptor. - Chemical-first · University of British Columbia · SGLT2 inhibitor · Diabetes
This drug targets the SGLT2 receptor to reduce glucose reabsorption in the kidneys. - FNC · Henan Genuine Biotech Co., Ltd. · SGLT2 inhibitor · Diabetes
FNC is a small molecule that targets the SGLT2 receptor. - Vitamin D3 plus Dapagliflozin · University Malaysia Sarawak · SGLT2 inhibitor · Diabetes
Vitamin D3 acts as a hormone receptor agonist, while Dapagliflozin inhibits the SGLT2 transporter. - TJO-002 · Taejoon Pharmaceutical Co., Ltd. · SGLT2 inhibitor · Diabetes
TJO-002 is a small molecule that targets the SGLT2 receptor. - X842 · Jiangsu Sinorda Biomedicine Co., Ltd · SGLT2 inhibitor · Diabetes
X842 is a small molecule that targets the SGLT2 receptor. - PM8002 · Biotheus Inc. · SGLT2 inhibitor · Diabetes
PM8002 is a small molecule that targets the SGLT2 receptor. - YL201 · MediLink Therapeutics (Suzhou) Co., Ltd. · SGLT2 inhibitor · Diabetes
YL201 is a small molecule inhibitor of the sodium-glucose cotransporter 2 (SGLT2). - Zibotentan/Dapagliflozin · AstraZeneca · SGLT2 inhibitor · Diabetes
Zibotentan/Dapagliflozin is a combination of a selective endothelin receptor antagonist and a sodium-glucose cotransporter 2 inhibitor. - PAAA · GlaxoSmithKline · SGLT2 inhibitor · Diabetes
PAAA is a small molecule that targets the SGLT2 receptor. - CPL-01 · Cali Pharmaceuticals LLC · SGLT2 inhibitor · Diabetes
CPL-01 is a small molecule that targets the SGLT2 receptor. - CTP0302-B · Taejoon Pharmaceutical Co., Ltd. · SGLT2 inhibitor · Diabetes
CTP0302-B is a small molecule that targets the SGLT2 receptor. - LBSA0103 · LG Life Sciences · SGLT2 inhibitor · Diabetes
LBSA0103 is a small molecule that targets the SGLT2 receptor. - PG201 tablet · PMG Pharm Co., Ltd · SGLT2 inhibitor · Diabetes
PG201 tablet is a small molecule that targets the SGLT2 receptor. - P-3074 · Polichem S.A. · SGLT2 inhibitor · Diabetes
P-3074 is a small molecule that targets the SGLT2 receptor. - FRSW117 · Jiangsu Gensciences lnc. · SGLT2 inhibitor · Diabetes
FRSW117 is a small molecule that targets the SGLT2 receptor. - JNS020QD · Janssen Pharmaceutical K.K. · SGLT2 inhibitor · Diabetes
JNS020QD is a small molecule that targets the SGLT2 receptor. - Tigerase® and best available care · AO GENERIUM · SGLT2 inhibitor · Diabetes
Tigerase works by inhibiting the activity of a specific enzyme. - SA-001 · Abbott · SGLT2 inhibitor · Diabetes
SA-001 is a small molecule that targets the SGLT2 receptor. - CDFR0612 · CTC Bio, Inc. · SGLT2 inhibitor · Diabetes
CDFR0612 is a small molecule that targets the SGLT2 receptor. - DW1026S · Daewon Pharmaceutical Co., Ltd. · SGLT2 inhibitor · Diabetes
DW1026S is a small molecule that targets the SGLT2 receptor. - THP-00105 · THPharm Corp. · SGLT2 inhibitor · Diabetes
THP-00105 is a small molecule that targets the SGLT2 receptor. - ZF2001 · Guangzhou Patronus Biotech Co., Ltd. · SGLT2 inhibitor · Diabetes
ZF2001 is a small molecule that targets the SGLT2 receptor. - UI05MSP015CT · Korea United Pharm. Inc. · SGLT2 inhibitor · Diabetes
This drug is a small molecule that targets the SGLT2 receptor. - AC-170 0% · Aciex Therapeutics, Inc. · SGLT2 inhibitor · Diabetes
AC-170 is a small molecule that targets the SGLT2 receptor. - NTI164 · Fenix Innovation Group · SGLT2 inhibitor · Diabetes
NTI164 is a small molecule that acts as a selective inhibitor of the SGLT2 transporter.